Debra Aker Willins

age ~61

from Waban, MA

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Connected to:

Novel Vector For C. Glabrata And The Use Thereof
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US Patent:

20020192827, Dec 19, 2002
Filed:

Feb 22, 2002
Appl. No.:

10/079818
Inventors:

Guillaume Cottarel - Arlington MA, US
Debra Willins - Watertown MA, US
International Classification:

C12N001/18
C12N015/74
US Classification:

435/484000, 435/320100, 435/254220
Abstract:

The present invention is directed to a vector for expressing a gene of interest in a Candida species. The vector of the present invention comprises promoter and terminator sequences from a native Candida gene. This vector can be used to complement deleted genes in a Candida species. The present invention is also directed to a method for identifying genes essential for growth of a Candida species. Additionally, the present invention is directed to a method for screening for anti-fungal compounds effective against Candida species.

Identification Of Cell Surface Proteins And Their Uses
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US Patent:

7241613, Jul 10, 2007
Filed:

Jun 5, 2003
Appl. No.:

10/455719
Inventors:

Debra A. Willins - Watertown MA, US
Arturo J. Morales - Arlington MA, US
Guillaume Cottarel - Cambridge MA, US
Qiandong Zeng - Belmont MA, US
Assignee:

Oscient Pharmaceuticals Corporation - Waltham MA
International Classification:

C12N 1/00
A61K 36/06
C12P 21/04
C07H 21/04
US Classification:

4352554, 435 6, 435243, 4352523, 4352541, 43525422, 4353201, 435 691, 435 697, 4242741, 4241841, 530300, 530350, 536 231, 536 237
Abstract:

The invention provides for novel polypeptides of species found on the cell wall of the organism. The invention further provides for methods of using these polypeptides, the genes encoding the polypeptides and fragments thereof for preparing antibodies, vaccines, therapeutic and diagnostic compositions.

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