Dennis J Mccarthy

US Patent:

7982038, Jul 19, 2011

Filed:

Sep 24, 2004

Appl. No.:

10/573133

Inventors:

Peter Dorff - Wilmington DE, US
John Gordon - Wilmington DE, US
John Richard Heys - Wilmington DE, US
Richard A Keith - Wilmington DE, US
Dennis J McCarthy - Wilmington DE, US
Mark A Smith - Wilmington DE, US
Eifion Phillips - Bothwyn PA, US

Assignee:

AstraZeneca AB

International Classification:

C07D 413/04
A61K 31/44

US Classification:

546 18, 514278, 514281

Abstract:

A radioactive compound having the formula:and pharmaceutically-acceptable salts thereof, wherein Rand Ar are as defined in the specification, enantiomers, in vivo-hydrolysable precursors, pharmaceutical compositions and formulations containing them, methods of using them to treat diseases and conditions either alone or in combination with other therapeutically-active compounds or substances, processes and intermediates used to prepare them and uses of them for diagnostic and analytic purposes.

US Patent:

20040259909, Dec 23, 2004

Filed:

Apr 16, 2004

Appl. No.:

10/492891

Inventors:

Dennis McCarthy - Wilmington DE, US
David Gurley - Wilmington DE, US

International Classification:

A61K031/4745
A61K031/424

US Classification:

514/305000, 514/375000

Abstract:

A method for treating fibromyalgia syndrome with an agonist of 7 nicotinic acetylcholine receptors.

US Patent:

20050129610, Jun 16, 2005

Filed:

Jun 24, 2004

Appl. No.:

10/877813

Inventors:

Martin Pomper - Baltimore MD, US
John Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter Dorff - Wilmington DE, US

International Classification:

A61K051/00
A61K031/4747
C07D491/14
C07F005/00

US Classification:

424001110, 514278000, 534011000, 546018000

Abstract:

The present invention relates to radiolabelled compounds particularly 1-azabicyclo[2.2.2]octane compounds (i.e., quinuclidine compounds) which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express the a7-nicotinic cholinergic receptor. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express a7-nicotinic cholinergic receptor to which the compounds of the invention have an affinity.

US Patent:

20100034741, Feb 11, 2010

Filed:

Jan 26, 2009

Appl. No.:

12/321951

Inventors:

Martin G. Pomper - Baltimore MD, US
John L. Musachio - Baltimore MD, US
Hong Fan - Lutherville Timonium MD, US
Robert F. Dannals - Sparks MD, US
Catherine Foss - Baltimore MD, US
Eifion Phillips - Wilmington DE, US
John Gordon - Wilmington DE, US
Dennis McCarthy - Wilmington DE, US
Richard Keith - Wilmington DE, US
Mark Smith - Wilmington DE, US
Richard Heys - Wilmington DE, US
Peter N. Dorff - Wilmington DE, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C07D 453/02
C07D 453/00
A61K 51/04
G01N 33/53

US Classification:

424 189, 546133, 546 83, 424 181, 424 185, 435 72

Abstract:

The present invention relates to radiolabelled compounds particularly 1-azabicyclo[2.2.2]octane compounds (i.e., quinuclidine compounds) which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express the α7-nicotinic cholinergic receptor. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express α7-nicotinic cholinergic receptor to which the compounds of the invention have an affinity.

US Patent:

20190190131, Jun 20, 2019

Filed:

Dec 18, 2017

Appl. No.:

15/845712

Inventors:

- Chicago IL, US
Dennis Kent McCarthy - Media PA, US

International Classification:

H01Q 1/28
B32B 15/08
B32B 27/20
H01Q 1/52

Abstract:

The embodiments described herein provide for composite panels that include elements that form one or more Radio Frequency (RF) antennas. The composite panels may be integrated along with other composite panels to form a composite structure for a vehicle. In some cases, the composite panels function both as elements of an RF antenna and as structural elements of the vehicle. In some cases, the composite panels function both as elements of an RF antenna and as a means for static charge dissipation. When operating as an RF antenna, the composite panels are inherently conformal with an outside surface of a composite structure.

US Patent:

20170301980, Oct 19, 2017

Filed:

Apr 20, 2015

Appl. No.:

14/691147

Inventors:

- Chicago IL, US
Dennis K. McCarthy - Media PA, US
Stacey A. Tyrrell - Glendale AZ, US
Courtney B. Kube - Scottsdale AZ, US

International Classification:

H01Q 1/28
B32B 5/02
H01Q 1/42
H01Q 1/32

Abstract:

A composite panel may include a structural first laminate including a first composite material opaque to electromagnetic radiation, the first laminate further including an outer perimeter edge and an inner perimeter edge, and a structural second laminate including a second composite material transparent to electromagnetic radiation, the second laminate being disposed within and physically joined with the first laminate along the inner perimeter edge.