Dennis Charles O'Brien

US Patent:

52468542, Sep 21, 1993

Filed:

Dec 16, 1991

Appl. No.:

7/807334

Inventors:

Dennis J. O'Brien - Ambler PA
Wolfgang K. Heiland - Trevose PA

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

C12M 304

US Classification:

435285

Abstract:

An attached growth biological reactor for the growth and harvesting of filamentous fungi. The reactor contains a rigid cylinder which is partially submerged and rotated in a biological medium containing nutrients for fungal growth and which as been inoculated with a filamentous fungal medium. The filamentous fungi attaches itself to and grows upon the cylinder wherein it is removed by use of a doctoring blade. The reactor can be operated in a continuous mode by continuously supplying oxygen and nutrients to the reactor.

US Patent:

52468429, Sep 21, 1993

Filed:

Oct 30, 1991

Appl. No.:

7/785375

Inventors:

Dennis J. O'Brien - Ambler PA
Edgar E. Stinson - Melrose Park PA
Eric W. Wessinger - Decatur IL
George A. Somkuti - Lansdale PA

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

C12P 764
C12N 114
C12N 100
A61K 3120

US Classification:

435134

Abstract:

A process for the production of 5,8,11,14,17 -eicosapentaenoic acid from filamentous fungi with lactose as a substrate. Preferred filamentous fungi include Pythium ultimum, Pythium debaryanum, Pythium sp, and Pythium irregulare, the preferred lactose source being whey.