Dennis E Prosen

age ~68

from Foster City, CA

Get Report
Also known as:
  • Dennis R Prosen
  • Denny E Prosen
Phone and address:
741 Niantic Dr, San Mateo, CA 94404
6503497517
Related to:
Connected to:

Dennis Prosen Phones & Addresses

  • 741 Niantic Dr, San Mateo, CA 94404 • 6503497517
  • Foster City, CA
  • South San Francisco, CA
  • Salinas, CA
  • San Juan Bautista, CA
  • Boulder, CO
  • Walnut Creek, CA
  • 741 Niantic Dr, Foster City, CA 94404 • 6508882464

Work

  • Company:
    Bd
    Dec 2015 to Jan 2017
  • Position:
    Principal scientist

Education

  • Degree:
    Doctorates, Doctor of Philosophy
  • School / High School:
    University of Colorado Boulder
  • Specialities:
    Chemistry

Skills

Dna Sequencing • Biotechnology • Molecular Biology • Pcr • Dna • Assay Development • Qpcr • Genetics • Genomics • Protein Purification • Purification • Life Sciences • Protein Chemistry • Biochemistry • R&D • Science • Sequencing • Protein Engineering • Lifesciences • Protein Expression • Cell • Proteomics • Real Time Polymerase Chain Reaction • Enzyme Kinetics • High Throughput Screening • Microarray • Polymerase Chain Reaction • Research and Development • Research • Fluorescence • Analysis • Genotyping • Protein Characterization

Languages

English

Industries

Biotechnology

Resumes

Dennis Prosen Photo 1

Dennis Prosen

view source
Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Bd Dec 2015 - Jan 2017
Principal Scientist
Natera May 2014 - Dec 2015
Staff Scientist
Natera Jan 2015 - Dec 2015
Principal Scientist
Natera Mar 2012 - Dec 2013
Senior Scientist
Life Technologies Mar 2010 - Nov 2011
Senior Staff Scientist, Enzymologist
Education:
University of Colorado Boulder
Doctorates, Doctor of Philosophy, Chemistry Bemidji State University
Bachelors, Bachelor of Science, Chemistry
Skills:
Dna Sequencing
Biotechnology
Molecular Biology
Pcr
Dna
Assay Development
Qpcr
Genetics
Genomics
Protein Purification
Purification
Life Sciences
Protein Chemistry
Biochemistry
R&D
Science
Sequencing
Protein Engineering
Lifesciences
Protein Expression
Cell
Proteomics
Real Time Polymerase Chain Reaction
Enzyme Kinetics
High Throughput Screening
Microarray
Polymerase Chain Reaction
Research and Development
Research
Fluorescence
Analysis
Genotyping
Protein Characterization
Languages:
English

Us Patents

  • Nucleic Acid Modifying Enzymes

    view source
  • US Patent:
    7670808, Mar 2, 2010
  • Filed:
    Apr 9, 2004
  • Appl. No.:
    10/821583
  • Inventors:
    Yan Wang - San Francisco CA, US
    Lei Xi - Foster City CA, US
    Dennis E. Prosen - Foster City CA, US
  • Assignee:
    Bio-Rad Laboratories, Inc. - Hercules CA
  • International Classification:
    C12P 19/34
    C12N 9/12
  • US Classification:
    435 911, 435194, 435183, 435455, 435 691
  • Abstract:
    This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzyme to bind and catalytically modify the nucleic acid.

  • Nucleic Acid Modifying Enzymes

    view source
  • US Patent:
    20030162173, Aug 28, 2003
  • Filed:
    May 30, 2001
  • Appl. No.:
    09/870353
  • Inventors:
    Yan Wang - San Francisco CA, US
    Lei Xi - Foster City CA, US
    Dennis Prosen - Foster City CA, US
  • Assignee:
    MJ Bioworks Incorporated - South San Francisco CA
  • International Classification:
    C12Q001/68
    C07H021/04
    C12P019/34
    C12N009/22
    C12P021/02
    C12N001/21
    C12N015/74
  • US Classification:
    435/006000, 435/091200, 435/069100, 435/199000, 435/320100, 435/252300, 536/023200
  • Abstract:
    This invention provides for an improved generation of novel nucleic acid modifying enzymes. The improvement is the fusion of a sequence-non-specific nucleic-acid-binding domain to the enzyme in a manner that enhances the ability of the enzyme to bind and catalytically modify the nucleic acid.

  • Methods And Compositions For Pcr

    view source
  • US Patent:
    20090263869, Oct 22, 2009
  • Filed:
    Aug 27, 2008
  • Appl. No.:
    12/198962
  • Inventors:
    Lei Xi - Foster City CA, US
    Dennis E. Prosen - Foster City CA, US
    Alexander A. Novikov - Union City CA, US
  • International Classification:
    C12P 19/34
    C12N 9/12
  • US Classification:
    435 912, 435194
  • Abstract:
    A modified thermostable Pol B DNA polymerase, produced by a reaction, under essentially aqueous conditions, of a thermostable Pol B DNA polymerase and a modifier reagent of Formula I wherein the reaction results in a thermally reversible inactivation of the thermostable Pol B DNA polymerase activity and the 3′-5′ exonuclease activity, which polymerase is suitable for hot-start PCR. Also disclosed are the method for the modification, a polynucleic acid amplification method and PCR reaction mixture and kit comprising the modified thermostable Pol B DNA polymerase.

  • Polymerization Of Nucleic Acids Using Activation By Polyphosphorolysis (App) Reactions

    view source
  • US Patent:
    20120196329, Aug 2, 2012
  • Filed:
    Dec 13, 2011
  • Appl. No.:
    13/324676
  • Inventors:
    Lei (Larry) XI - Foster City CA, US
    Paul Kenney - Sunnyvale CA, US
    Zhaochun Ma - Sunnyvale CA, US
    Dennis Prosen - Foster City CA, US
    Stephen Hendricks - Los Gatos CA, US
    Roland Nagel - Santa Cruz CA, US
  • Assignee:
    LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
  • International Classification:
    C12P 19/34
  • US Classification:
    435 912, 435 915, 435 9151
  • Abstract:
    This disclosure relates to methods of performing activation by polyphosphorolysis (APP) reactions using at least one of the polyphosphorylating agents triphosphate, polyphosphate, imidodiphosphate, thiodiphosphate (or μ-monothiopyrophosphate), and related compounds.

  • Primers For Immune Repertoire Profiling

    view source
  • US Patent:
    20210355484, Nov 18, 2021
  • Filed:
    May 13, 2021
  • Appl. No.:
    17/320052
  • Inventors:
    - Franklin Lakes NJ, US
    Katherine Lazaruk - San Jose CA, US
    Dennis Prosen - San Jose CA, US
    Ricelle A. Acob - San Jose CA, US
    Kai Liu - San Jose CA, US
  • International Classification:
    C12N 15/10
    C12Q 1/6858
    C07K 14/705
    C07K 14/725
  • Abstract:
    Disclosed herein include systems, methods, compositions, and kits for immune repertoire profiling. There are provided, in some embodiments, primer panels enabling the determination of the nucleotide sequence of the complete variable region of nucleic acids encoding mouse B cell receptor (BCR) and T cell receptor (TCR) polypeptides. In some embodiments, the method comprises single cell transcriptomic analysis.

  • Precise Delivery Of Components Into Fluids

    view source
  • US Patent:
    20200299672, Sep 24, 2020
  • Filed:
    Feb 24, 2020
  • Appl. No.:
    16/799464
  • Inventors:
    - Menlo Park CA, US
    Sixing Li - Mountain View CA, US
    Dennis Prosen - Foster City CA, US
  • International Classification:
    C12N 15/10
  • Abstract:
    Disclosed herein include systems, apparatuses, devices, and methods for introducing one or more components into a fluid. A first fluid and a second fluid can be co-injected into a fluidic channel of a flow cell. In some embodiments, the first fluid and a second fluid are immiscible (e.g. an aqueous buffer and a non-aqueous liquid). In some embodiments, the second fluid is less dense than the first fluid.

  • Oligonucleotides Associated With Antibodies

    view source
  • US Patent:
    20200232032, Jul 23, 2020
  • Filed:
    Jan 21, 2020
  • Appl. No.:
    16/747737
  • Inventors:
    - San Jose CA, US
    Katherine Lazaruk - San Jose CA, US
    Dennis E. Prosen - San Jose CA, US
    Devon Jensen - San Jose CA, US
    David Rosenfeld - San Jose CA, US
    Janice H. Lai - San Jose CA, US
    James Ghadiali - San Jose CA, US
    Christina Chang - San Jose CA, US
  • International Classification:
    C12Q 1/6876
    C12Q 1/6806
    C12Q 1/6853
  • Abstract:
    Disclosed herein include systems, methods, compositions, and kits for determining protein expression and gene expression simultaneously and for sample indexing. In some embodiments, an oligonucleotide associated with a cellular component-binding reagent (e.g., an antibody) comprises one or more of a unique molecular label sequence, a primer adapter, antibody-specific barcode sequence, an alignment sequence, and/or a poly(A) sequence. In some embodiments, the oligonucleotide is associated with the cellular component-binding reagent via a linker (e.g., 5AmMC12).

  • Compositions And Methods For Detection Of Nucleic Acid Mutations

    view source
  • US Patent:
    20190185913, Jun 20, 2019
  • Filed:
    Jun 30, 2017
  • Appl. No.:
    16/309271
  • Inventors:
    - San Carlos CA, US
    Joshua BABIARZ - Castro Valley CA, US
    Raheleh SALARI - San Carlos CA, US
    Tudor Pompiliu CONSTANTIN - Berkley CA, US
    Onur SAKARYA - Redwood City CA, US
    Dennis PROSEN - Foster City CA, US
    Alexander OLSON - Fremont CA, US
    Scott DASHNER - Sunnyvale CA, US
    Nikolay SERGEEV - Foster City CA, US
    Matthew Micah HILL - Belmont CA, US
  • Assignee:
    Natera, Inc. - San Carlos CA
  • International Classification:
    C12Q 1/686
    C12Q 1/6853
    C12Q 1/6886
  • Abstract:
    The invention provides methods and compositions for detecting a mutation in a target gene in a sample of blood or a fraction thereof, including in certain examples, a fraction that includes circulating tumor DNA. The methods can include a tiling PCR reaction, for example a one-sided multiplex tiling reaction. Virtually any type of mutation can be detected with the methods and compositions. In certain embodiments, gene fusions are detected. Improved PCR methods, especially for performing nested multiplex PCR reactions are provided.

Youtube

Jim Blasingame with Bob Prosen June 28, 2011

Jim Blasingame with Bob Prosen June 28, 2011

What separates America from the rest of the world? Inspiration. Bob Pr...

  • Category:
    People & Blogs
  • Uploaded:
    28 Jun, 2011
  • Duration:
    6m 37s
Get Report for Dennis E Prosen from Foster City, CA, age ~68
Control profile