Dmitriy V Ivashin

US Patent:

20120326020, Dec 27, 2012

Filed:

Mar 28, 2012

Appl. No.:

13/506120

Inventors:

Dmitriy V. Ivashin - Peabody MA, US
Saïd Boumsellek - San Diego CA, US

International Classification:

H01J 49/04

US Classification:

250282, 250288

Abstract:

A tandem instrument using a variable frequency pulsed ionization source and two separation techniques, low (IMS) and high (FAIMS) field mobility is provided. The analytical stage features a field driven FAIMS cell embedded on-axis within the IMS drift tube. The FAIMS cell includes two parallel grids of approximately the same diameter as the IMS rings and can be placed anywhere along the drift tube and biased according to their location in the voltage divider ladder to create the same IMS field. The spacing between the grids constitutes the analytical gap where ions are subject, in addition to the drift field, to the asymmetric dispersive field of the FAIMS. The oscillatory motion performed during the high and low voltages of the asymmetric waveform separates the ions according to the difference in their mobilities.

US Patent:

20120273669, Nov 1, 2012

Filed:

Apr 27, 2011

Appl. No.:

13/066894

Inventors:

Dmitriy V. Ivashin - Peabody MA, US
Saïd Boumsellek - San Diego CA, US

International Classification:

H01J 49/04
H01J 49/34

US Classification:

250282, 250288

Abstract:

Using combined orthogonal techniques, such as low (IMS) and high (FAIMS) field mobility techniques, offers several advantages to ion detection and analysis techniques including low cost, no vacuum required, and the generation of 2-D spectra for enhanced detection and identification. Two analytical devices may be operated in different modes, which results in overall flexibility by adapting the hyphenated instrument to the application's requirements. With the IMS-FAIMS hardware level flexibility, the instruments may be configured and optimized to exploit different trade-offs suitable for a variety of detection scenarios of for different lists of target compounds.

US Patent:

20220276202, Sep 1, 2022

Filed:

Apr 25, 2022

Appl. No.:

17/727969

Inventors:

- Tewksbury MA, US
Troy Velazquez - Salem NH, US
Anatoly Lazarevich - Needham MA, US
Dmitriy Ivashin - Peabody MA, US
Andrew Anderson - Westford MA, US

International Classification:

G01N 27/622
G01N 27/68
H01J 49/00
G01N 27/626

Abstract:

A chemical trace detection system includes: a drift tube; a detector disposed within the drift tube; a voltage source to produce an electrical field in the drift tube; an ionizer to establish an ionization region adjacent to the electrical field; and a desorber including a sample holder to hold a sample in or adjacent to the ionization region and a sample heater to desorb particles of the sample held in the sample holder such that the desorbed particles are introduced directly into the ionization region from the sample holder to form ionized particles that are forced toward the detector by the electrical field. A regenerable dryer assembly for supplying dry drift gas to an ion mobility spectrometer is also provided that includes a regenerable dessicant material.

US Patent:

20200284757, Sep 10, 2020

Filed:

May 21, 2020

Appl. No.:

16/880643

Inventors:

- Tewksbury MA, US
Troy Velazquez - Salem NH, US
Anatoly Lazarevich - Needham MA, US
Dmitriy Ivashin - Peabody MA, US
Andrew Anderson - Westford MA, US

International Classification:

G01N 27/62
G01N 27/68
H01J 49/00

Abstract:

A chemical trace detection system includes: a drift tube; a detector disposed within the drift tube; a voltage source to produce an electrical field in the drift tube; an ionizer to establish an ionization region adjacent to the electrical field; and a desorber including a sample holder to hold a sample in or adjacent to the ionization region and a sample heater to desorb particles of the sample held in the sample holder such that the desorbed particles are introduced directly into the ionization region from the sample holder to form ionized particles that are forced toward the detector by the electrical field. A regenerable dryer assembly for supplying dry drift gas to an ion mobility spectrometer is also provided that includes a regenerable dessicant material.

US Patent:

20200072791, Mar 5, 2020

Filed:

Aug 31, 2018

Appl. No.:

16/119472

Inventors:

- Woburn MA, US
Troy Velazquez - Salem NH, US
Anatoly Lazarevich - Needham MA, US
Dmitriy Ivashin - Peabody MA, US
Andrew Anderson - Westford MA, US

International Classification:

G01N 27/62
G01N 27/68
H01J 49/00

Abstract:

A chemical trace detection system includes: a drift tube; a detector disposed within the drift tube; a voltage source to produce an electrical field in the drift tube; an ionizer to establish an ionization region adjacent to the electrical field; and a desorber including a sample holder to hold a sample in or adjacent to the ionization region and a sample heater to desorb particles of the sample held in the sample holder such that the desorbed particles are introduced directly into the ionization region from the sample holder to form ionized particles that are forced toward the detector by the electrical field. A regenerable dryer assembly for supplying dry drift gas to an ion mobility spectrometer is also provided that includes a regenerable dessicant material.

US Patent:

20160148794, May 26, 2016

Filed:

Dec 2, 2015

Appl. No.:

14/956485

Inventors:

- Wilmington MA, US
Troy A. Velazquez - Somerville MA, US
Dmitriy V. Ivashin - Peabody MA, US
Said Boumsellek - San Diego CA, US

International Classification:

H01J 49/02
H05K 3/00
H05K 3/40
G01N 27/62

Abstract:

For ion mobility spectrometry applications, a desired shape of a sensor structure may be created by forming a desired shape from a ceramic material, such as aluminum nitride. In various embodiments, the sensor structure may be formed using discrete individual ceramic sheets and/or from a preformed ceramic tube. Via holes are formed into the sensor structure to provide for efficient circuitry configurations of the IMS drift tube and/or providing electrical connections between the interior and exterior of the drift tube.

US Patent:

20150001387, Jan 1, 2015

Filed:

Jun 27, 2014

Appl. No.:

14/317133

Inventors:

- Wilimington MA, US
Dmitriy V. Ivashin - Peabody MA, US

International Classification:

H01J 49/18

US Classification:

250282, 250423 R, 250288

Abstract:

Devices and techniques for ion analysis, including ion mobility separation and mass spectrometry, are provided using a dual polarity spark ion source and having the flexibility required to optimize the detection performance for a broad range of illicit substances with different physical and chemical properties. In various embodiments, the volatility and electro-chemical aspects may be addressed by the system described herein by performing real-time detection of compounds detectable in both positive and negative polarities and/or prioritizing spectra acquisition in a given polarity due to the high volatility and therefore short residence of certain target compounds.

US Patent:

20140239174, Aug 28, 2014

Filed:

Feb 26, 2014

Appl. No.:

14/190785

Inventors:

- Wilmington MA, US
Troy A. Velazquez - Somerville MA, US
Dmitriy V. Ivashin - Peabody MA, US
Said Boumsellek - San Diego CA, US

Assignee:

Implant Sciences Corporation - Wilmington MA

International Classification:

H01J 49/02
H01J 49/00
G01N 27/62

US Classification:

250288, 2503361, 264132

Abstract:

For ion mobility spectrometry applications, a desired shape of a sensor structure may be created by forming a desired shape from a ceramic material, such as aluminum nitride. In various embodiments, the sensor structure may be formed using discrete individual ceramic sheets and/or from a preformed ceramic tube. Via holes are formed into the sensor structure to provide for efficient circuitry configurations of the IMS drift tube and/or providing electrical connections between the interior and exterior of the drift tube.