Donald M Elliott

US Patent:

60963158, Aug 1, 2000

Filed:

Jun 6, 1995

Appl. No.:

8/469923

Inventors:

Daniel H. Zimmerman - Bethesda MD
Donald A. Elliott - Bethesda MD

Assignee:

Cel Sci Corporation - Alexandria VA

International Classification:

C07K 100

US Classification:

4241931

Abstract:

The present invention relates to a heterofunctional cellular immunological reagent comprising at least two T cell specific binding ligands covalently linked together, wherein one of the T cell specific binding ligands binds to a specific class or subclass of T cells and another of the T cell specific binding ligands is an antigen associated with disease or a causative agent of disease, or epitope thereof. The present invention also relates to vaccines containing the heterofunctional cellular immunological reagents and methods for the use of the same.

US Patent:

56523424, Jul 29, 1997

Filed:

Dec 8, 1994

Appl. No.:

8/354751

Inventors:

Daniel H. Zimmerman - Bethesda MD
Donald A. Elliott - Bethesda MD

Assignee:

Cel-Sci Corporation - Alexandria VA

International Classification:

C07K 14705
A61K 39385

US Classification:

530403

Abstract:

The present invention relates to a heterofunctional cellular immunological reagent comprising at least two T cell specific binding ligands covalently linked together, wherein one of the T cell specific binding ligands binds to a specific class or subclass of T cells and another of the T cell specific binding ligands is an antigen associated with disease or a causative agent of disease, or epitope thereof. The present invention also relates to vaccines containing the heterofunctional cellular immunological reagents and methods for the use of the same.

US Patent:

50045830, Apr 2, 1991

Filed:

Aug 8, 1988

Appl. No.:

7/229503

Inventors:

Vinodhini Guruswamy - Bethesda MD
Donald A. Elliott - Bethesda MD

Assignee:

MedTest Systems, Inc. - College Park MD

International Classification:

G01N 2127
G01N 2163
G01N 27333

US Classification:

422 58

Abstract:

The apparatus employs a method for accurate, reproducible analytical solution evaluation eliminating the need for a reference sensor by determining the activity of selected species employing species specific sensors and species combination sensors in conjunction with Nernst-type equations. The apparatus includes sensor structures for elimination of edge effects to signals thereby yielding accurate, reproducible measurements, and a cartridge structure adapted to incorporate an array of the new sensors for employment of the new method where the cartridge is particularly adapted for miniaturization, maintaining a fixed volume of solution for analysis and providing an anaerobic testing environment. Lastly, a compact instrument embodying miniaturization especially adapted for field use and use of the cartridge is provided herein.