Agios Pharmaceuticals
Senior Scientist
Abbvie Sep 2012 - Jun 2017
Senior Scientist
The Wistar Institute Feb 2008 - Aug 2012
Postdoctoral Fellow
Drexel University Aug 2004 - Dec 2007
Research Fellow and Graduate Student
Texas Tech University Jul 1996 - Jul 2000
Research Fellow and Student
Education:
Drexel University 2007
Doctorates, Doctor of Philosophy, Biomedical Engineering
Drexel University 2005
Master of Science, Masters, Biomedical Engineering
Texas Tech University 1994 - 2000
Bachelors, Bachelor of Science, Chemical Engineering
Skills:
Flow Cytometry Multi Color Flow Cytometry Cell Biology Assay Development Animal Models Cell Culture Mouse Models of Autoimmunity Ex Vivo Assays of T Cell Activation and Function Isolation and Culture of Immune Cells In Vitro Cd4+ T Cell Differentiation Adoptive Transfer of T Cells Generation of Bone Marrow Chimeric Mice Survival Surgery
E. I. Du Pont De Nemours and Company - Wilmington DE
International Classification:
C08K 334
US Classification:
260 4246
Abstract:
Polypropylene compositions having high ignition resistance, flex modulus, and impact resistance are obtained by blending polypropylene homopolymer, a propylene/ethylene copolymer, an EPM or EPDM elastomer having an ethylene content of about 50-65 weight percent and a Mooney viscosity of 35-80, mica, a commercial chlorinated fire retardant, and antimony trioxide in defined proportions. These compositions are particularly suitable for electrical wire insulation and other applications where toughness, stiffness, and ignition resistance are important.
E. I. du Pont de Nemours and Company - Wilmington DE
International Classification:
A61K 3158 C07J 100 C07J 1700 G01N 100
US Classification:
424 88
Abstract:
Estriol and estradiol glycidyl ethers, immunogenic conjugates thereof and processes for their preparation are provided. The immunogenic conjugates are useful for eliciting and purifying antibodies and in performing immunoassays for estriol and estradiol.
Method For Specific Binding Assays Using A Releasable Ligand
Donald M. Simons - Wilmington DE Susan Y. Tseng - Hockessin DE David M. Obzansky - Elkton MD
Assignee:
E. I. DuPont de Nemours and Company - Wilmington DE
International Classification:
G01N 33543
US Classification:
436518
Abstract:
Immunoassays and DNA probe assays utilizing a non-immune, reversible binding displacement system are provided. In the assay, a releasable ligand, a binding partner for the releasable ligand, an analyte of interest, an analytically detectable (reporter) group, and at least one binding partner for the analyte, are first attached to an insoluble phase so as to form reporter-labeled complex bound to an insoluble phase, followed by the addition of a displacer ligand which displaces the releasable ligand along with some portion of the reporter-labeled complex, so that the released reporter is analytically detectable in a free liquid medium and can be related to the concentration of analyte in the sample.
Homogeneous Assays Using Avidin-Binding Azo Reagents
E. I. Du Pont de Nemours and Company - Wilmington DE
International Classification:
C08K 534 C08K 551 C08K 304 C08K 532
US Classification:
252606
Abstract:
Certain filled propylene polymer compositions, especially propylene homopolymers filled with a carbon black (10-50 parts per 100 parts of polymer) and containing about 30-50 parts of intumescent fire-retardant obtained by heating a mixture of a polyol, a phosphorus acid, and melamine have very high ignition resistance and desirable physical properties. When usual inorganic fillers are used, instead of carbon black, good ignition resistance is not obtained. Carbonaceous materials other than carbon blacks, for example, acetylene blacks, graphite, and so-called Austin black reduce or completely counteract the fire-retardant activity of the intumescent fire retardant. Filled propylene polymer compositions of this invention are particularly suitable in applications where the fire hazard is particularly great, for example, in automotive parts under the hood and in electrical applications.
Avidin-Binding Fluorescing And Quenching Reagent For Use In Homogeneous Assays
This invention relates to quinidine derivatives and immunogenic conjugates and reporter conjugates prepared therefrom. The immunogenic conjugates and reporter conjugates are useful for eliciting antibodies and for performing immunoassays for quinidine. A particle agglutination immunoassay for quinidine is also provided.