The present invention relates to the use of these cyclophilins, hereinafter referred to as âtyrosine-containingâ cyclophilins, in a method for identifying compounds capable of binding to and/or inhibiting the enzymatic activity of these proteins. Such compounds may be further screened for their ability to inhibit parasites which are not susceptible to the anti-parasitic effects of CsA.
Tyrosine-Containing Cyclophilin And Related Methods
Clotilde K. S. Carlow - Cambridge MA Xiqiang Hong - Danvers MA Dong Ma - Hamilton MA
Assignee:
New England Biolabs, Inc. - Beverly MA
International Classification:
C07K 100
US Classification:
530350
Abstract:
The present invention relates to the use of these cyclophilins, hereinafter referred to as `tyrosine-containing` cyclophilins, in a method for identifying compounds capable of binding to and/or inhibiting the enzymatic activity of these proteins. Such compounds may be further screened for their ability to inhibit parasites which are not susceptible to the anti-parasitic effects of CsA.
Provided herein is a reverse transcriptase mixture comprising a reverse transcriptase and a colored dye at a concentration in the range of 0.003%-1% (v/w). The colored dye may be visually observed during transfer of the mix from one vessel to another and addition of the mix to another mix can be confirmed by eye by observing the colored dye.
Provided herein is a reverse transcriptase mixture comprising a reverse transcriptase and a colored dye at a concentration in the range of 0.003%-1% (v/w). The colored dye may be visually observed during transfer of the mix from one vessel to another and addition of the mix to another mix can be confirmed by eye by observing the colored dye.
Name / Title
Company / Classification
Phones & Addresses
Dong Myung Ma
Dong Ma MD Physical Medicine
400 E 34 St, New York, NY 10016 2122636338
Dong Ma Nurse
East Shore Women's Care, PC Medical Doctor's Office
3907 Prince St, Flushing, NY 11354
Dong Ma Nurse
East Shore Medical Supply, Inc Whol Durable Goods
3907 Prince St, Flushing, NY 11354
Medicine Doctors
Dr. Dong M Ma, New York NY - MD (Doctor of Medicine)