Dong Hee Shin

US Patent:

20210114036, Apr 22, 2021

Filed:

Apr 30, 2019

Appl. No.:

17/051717

Inventors:

- Baltimore MD, US
Dong Jin SHIN - Baltimore MD, US
Alexander Y. TRICK - Baltimore MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

B01L 7/00
G01N 35/00

Abstract:

Devices for assaying a biomolecule from a sample, including: a cartridge assembly structured to accept and secure a magnetofluidic cartridge to be used for the assaying, and a magnetic particle manipulation assembly arranged proximate the cartridge assembly, the magnetic particle manipulation assembly having a pair of magnets arranged to be on opposing sides of said magnetofluidic cartridge and which are substantially aligned along a line that will be transverse to the magnetofluidic cartridge such that the line can be aligned with a well in the magnetofluidic cartridge, and methods of using and assembling such devices.

US Patent:

20150118740, Apr 30, 2015

Filed:

Oct 24, 2014

Appl. No.:

14/523412

Inventors:

- Baltimore MD, US
Dong Jin Shin - Baltimore MD, US

International Classification:

B01L 3/00
C12Q 1/68

US Classification:

4352872, 156182, 264400

Abstract:

Provided is a sample processing cartridge. The sample processing cartridge can include a housing and a channel disposed in the housing. The housing can include a sample inlet for receiving at least one biological sample. The channel can in fluidic communication with the sample inlet and can be defined by an upper surface and a lower surface. The upper surface can include a hydrophilic portion and a hydrophobic portion. The lower surface can include a hydrophilic portion and a hydrophobic portion. The hydrophilic and hydrophobic portions of the upper and lower surfaces of the channel can be configured to isolate at least one aqueous reagent.

US Patent:

20140206007, Jul 24, 2014

Filed:

Jan 18, 2013

Appl. No.:

13/745511

Inventors:

- Baltimore MD, US
Chi-Han Chiou - Baltimore MD, US
Dong Jin Shin - Baltimore MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C12Q 1/68

US Classification:

435 612, 4352872

Abstract:

A microfluidic system includes a microfluidic cartridge and an electromagnetic droplet actuator arranged proximate the microfluidic cartridge. The microfluidic cartridge includes a plurality of droplet wells with topological barrier structures between adjacent wells. The topological barrier structures are configured to allow magnetic particles and material attached to the magnetic particles to pass between adjacent wells while confining droplets within respective wells. The electromagnetic droplet actuator includes a plurality of electromagnetic components arranged to provide an electronically selectable magnetic field pattern to actuate movement of a plurality of magnetic particles when contained within at least one droplet in at least one of the plurality of droplet wells.