Donn G Wishka from Middletown, MD, age 65

Substituted-Heteroaryl-7-Aza[2.2.1]Bicycloheptanes For The Treatment Of Disease
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US Patent:

6562816, May 13, 2003
Filed:

Aug 14, 2002
Appl. No.:

10/218772
Inventors:

Donn G. Wishka - Kalamazoo MI
Jason K. Myers - Kalamazoo MI
Bruce N. Rogers - Portage MI
Eric Jon Jacobsen - Richland MI
David W. Piotrowski - Portage MI
Jeffrey W. Corbett - Portage MI
Alice L. Bodnar - Kalamazoo MI
Assignee:

Pharmacia Upjohn Company - Kalamazoo MI
International Classification:

A61K 315377
US Classification:

5142332, 514413, 544143, 546167, 546200, 5462697, 5462704, 5462714, 5462767, 548131, 548136, 548142, 548143, 548214, 548225, 548227, 548228, 548229, 548181, 548236, 548248, 5483121, 548453
Abstract:

The invention provides compounds of Formula I: compounds of the Formula I: wherein R , R , R , R , X, and W are defined herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which 7 is known to be involved.

Quinuclidine-Substituted Hetero-Bicyclic Aromatic Compounds For The Treatment Of Disease
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US Patent:

6828330, Dec 7, 2004
Filed:

Jun 6, 2002
Appl. No.:

10/163565
Inventors:

Daniel Patrick Walker - Kalamazoo MI
Donn G. Wishka - Kalamazoo MI
David W. Piotrowski - Portage MI
Assignee:

Pharmacia Upjohn Company - Kalamazoo MI
International Classification:

A61K 31439
US Classification:

514305, 546133, 546115, 546114, 546113, 514303, 514302, 514301, 514300, 514299
Abstract:

The invention provides compounds of Formula I: wherein W is a bicyclic moiety and is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful to treat diseases or conditions in which 7 is known to be involved.

N-(Azabicyclo Moieties)-Substituted Hetero-Bicyclic Aromatic Compounds For The Treatment Of Disease
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US Patent:

6849620, Feb 1, 2005
Filed:

Oct 17, 2002
Appl. No.:

10/272802
Inventors:

Daniel Patrick Walker - Kalamazoo MI, US
Eric Jon Jacobsen - Richland MI, US
David W. Piotrowski - Portage MI, US
Brad A. Acker - Kalamazoo MI, US
Donn G. Wishka - Kalamazoo MI, US
Jeffrey W. Corbett - Portage MI, US
Mark R. Rauckhorst - Portage MI, US
Assignee:

Pfizer Inc - New York NY
International Classification:

A61K 31435
A61K 3144
C07D45300
C07D47108
C07D48708
US Classification:

514214, 514299, 514301, 514302, 514303, 514305, 514367, 514373, 514375, 514379, 514394, 514403, 514413, 540582, 546112, 546114, 546115, 546118, 546120, 546133, 548159, 548207, 548217, 548241, 5483061, 548452, 548454
Abstract:

The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals in which α7 is known to be involved.

Fused Bicyclic-N-Bridged-Heteroaromatic Carboxamides For The Treatment Of Disease
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US Patent:

6858613, Feb 22, 2005
Filed:

Feb 14, 2003
Appl. No.:

10/366855
Inventors:

Bruce N. Rogers - Portage MI, US
David W. Piotrowski - Portage MI, US
Daniel Patrick Walker - Kalamazoo MI, US
Eric Jon Jacobsen - Richland MI, US
Brad A. Acker - Kalamazoo MI, US
Donn G. Wishka - Kalamazoo MI, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

A61K031/4985
A61K031/519
A61K031/439
C07D453/02
C07D471/04
US Classification:

514250, 514249, 5142591, 5142593, 51425931, 514267, 514294, 514299, 514300, 514303, 514305, 544281, 544282, 544349, 544350, 544252, 544256, 546112, 546118, 546121, 546133, 546135, 546 94
Abstract:

The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat conditions or diseases in which α7 is known to be involved.

Azabicyclic-Substituted Fused-Heteroaryl Compounds For The Treatment Of Disease
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US Patent:

6911543, Jun 28, 2005
Filed:

Oct 1, 2002
Appl. No.:

10/262257
Inventors:

Daniel Patrick Walker - Mystic CT, US
David W. Piotrowski - Waterford CT, US
Eric Jon Jacobsen - Chesterfield MO, US
Brad A. Acker - Saint Charles MO, US
Donn G. Wishka - Mystic CT, US
Steven Charles Reitz - Holland OH, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07D491/048
C07D495/04
US Classification:

546 80, 546 86, 546 87, 546 89, 546113, 546114, 546115, 546116, 540582
Abstract:

The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals in which α7 is known to be involved.

Azabicyclic Compounds For The Treatment Of Disease
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US Patent:

7001900, Feb 21, 2006
Filed:

Feb 14, 2003
Appl. No.:

10/366894
Inventors:

Eric Jon Jacobsen - Richland MI, US
Jason K. Myers - Kalamazoo MI, US
Daniel Patrick Walker - Kalamazoo MI, US
Donn G. Wishka - Kalamazoo MI, US
Steven Charles Reitz - Toledo OH, US
David W. Piotrowski - Portage MI, US
Brad A. Acker - Kalamazoo MI, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

A61K 31/55
A61K 31/506
A61K 31/439
C07D 471/08
C07D 487/08
US Classification:

51421403, 514256, 514299, 514304, 514305, 540582, 544335, 544333, 546112, 546125, 546135
Abstract:

The invention provides compounds of Formula I: wherein Azabicyclo is W is a six-membered heterocyclic ring system having 1–2 nitrogen atoms or a 10-membered bicyclic-six-six-fused-ring system having up to two nitrogen atoms within either or both rings, provided that no nitrogen is at a bridge of the bicyclic-six-six-fused-ring system, and further having 1–2 substitutents independently selected from R. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals to treat diseases or conditions in which α7 is known to be involved.

Quinuclidines-Substituted-Multi-Cyclic-Heteroaryls For The Treatment Of Disease
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US Patent:

7067515, Jun 27, 2006
Filed:

Jun 6, 2002
Appl. No.:

10/163564
Inventors:

Donn G. Wishka - Kalamazoo MI, US
Steven Charles Reitz - Toledo OH, US
David W. Piotrowski - Portage MI, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07D 453/02
A61K 31/439
US Classification:

5142282, 5142338, 51425304, 514301, 514302, 514305, 544 61, 544127, 544362, 546114, 546115, 546116, 546133
Abstract:

The invention provides compounds of Formula I:.

1-Pyrazole And 1-Pyrrole-Azabicyclic Compounds For The Treatment Of Disease
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US Patent:

7176198, Feb 13, 2007
Filed:

Jul 25, 2003
Appl. No.:

10/627140
Inventors:

David W. Piotrowski - Portage MI, US
Eric Jon Jacobsen - Richland MI, US
Brad A. Acker - Kalamazoo MI, US
Daniel Patrick Walker - Kalamazoo MI, US
Donn G. Wishka - Kalamazoo MI, US
Assignee:

Pfizer Inc. - New York NY
International Classification:

A61K 31/381
A61K 31/55
A61K 31/444
C07D 221/02
C07D 223/14
US Classification:

51421403, 514299, 514399, 514413, 514406, 540582, 540585, 548452, 5483647, 546112, 5462754
Abstract:

The invention provides compounds of Formula I:.