Dorothy J Plummer

US Patent:

20090246868, Oct 1, 2009

Filed:

Dec 10, 2004

Appl. No.:

10/583014

Inventors:

Ene Allikmets - Cornwall on Hudson NY, US
Amy Nichols - Warwick NY, US
Dorothy Plummer - Florida NY, US

Assignee:

Wyeth - Madison NJ

International Classification:

C12N 5/06
C12N 5/00

US Classification:

435364, 435404, 435374

Abstract:

A serum-free Vero cell banking process provides a standardized and consistent way to generate reliable and stable cell banks for viral vaccine production. The substitution of animal-derived substances with plant-derived substances in the growth and freezing media increases the viability of the cells upon thawing and reduces their recovery time, thereby allowing a more precise schedule for manufacturing and more consistent processes.