Joerg Deerberg - Bear DE Douglas D. McLeod - Kingston NJ Tai-Yuen Yue - Bear DE
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D21158
US Classification:
546244, 549342, 549425, 560156
Abstract:
A novel process for the asymmetric synthesis of substituted cyclic -amino-carboxylates of the type shown in the specification from appropriate -enamino-ester starting materials is described. These compounds are useful as intermediates for MMP and TACE inhibitors.
Charlotte Towell, Kenneth Colley, Edward Wood, Celia Bagley, Dorothy Nelson, Karen Bergstrom, Dennis Murphy, Marjorie Bartholomew, Jerry Ebensteiner, Charles Martin