William Paul Peters - Fernandina Beach FL, US Brian Huber - Durham NC, US Douglas Scott Tyler - Hillsborough NC, US
Assignee:
ADHEREX TECHNOLOGIES, INC. - Ottawa DEPARTMENT OF VETERANS AFFAIRS - Washington DC
International Classification:
A61K 38/12 A61K 31/197 A61P 35/00
US Classification:
514 9, 514564, 514 2
Abstract:
Improved methods for treating cancer which employ combinations comprising cadherin antagonists with certain anticancer agents or treatments are provided. The methods of the invention involve the administration of cadherin antagonist before, concurrent with, or after, administration of an anticancer agent or treatment and provide unexpectedly improved therapeutic benefit in the treatment of tumors growing in vivo.
Medicine Doctors
Dr. Douglas S Tyler, Durham NC - MD (Doctor of Medicine)
Appendectomy, Laparoscopic Colectomy Dressing and/or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy) Enterostomy (Laparoscopic or Open) Esophagectomy (Esophagogastrostomy, Esophagojejunostomy) Excision of Tumor of Stomach Excision, Shaving, or Destruction of Skin and Subcutaneous Tissue (incl. Mohs Micrographic Surgery), Tissue Transfer Gallbladder Removal, Laparoscopic Gastrectomy Incisional/Ventral Hernia Repair, Open Inguinal Hernia Repair, Open Intestinal Transplant (incl. Enterectomy) Laparotomy Lymph Node Biopsy or Excision Orchiectomy Pancreatectomy (incl. Pancreas Transplant & Whipple Procedure) Peripheral Artery Catheterization Removal or Destruction of Rectal or Intestinal Tumor (incl. Colonoscopy, Proctosigmoidoscopy, Sigmoidoscopy & Control of Hemorrhage) Splenectomy Splenectomy and Splenorrhaphy Tracheal Surgery Transendoscopic Stent Placement
Conditions:
Adrenal Gland Cancer Anal and Rectal Cancer Appendicitis Biliary Atresia Breast Cancer Breast Lump/Mass Carcinoma in Situ Cholecystitis and Gallstones Colorectal Cancer Diaphragmatic/Hiatal Hernia Esophageal Cancer Gallbladder & Biliary Tract Cancer Hemorrhoids Incisional Hernia Inguinal Hernia Intestinal Abscess Intestinal Obstruction Lipomas Liver Cancer Lung Cancer Neuroendocrine Tumors Pancreatic Cancer Peripheral Arterial Aneurysm and Dissection Peripheral Vascular Disease (PAD, PVD) Pyloric Stenosis Secondary Malignancies Second-Degree Burns Soft Tissue Sarcoma Stomach and Small Intestine Cancer Ulcerative Colitis Umbilical Hernia Varicose Veins Ventral Hernia
Certifications:
General Surgery, 2000
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School Dartmouth College Graduated: 1985 Medical School Duke University Hospital Graduated: 1985 Medical School MD Anderson Ctr Graduated: 1985
Dr. Tyler graduated from the SUNY Downstate Medical Center College of Medicine in 1979. He works in Santa Monica, CA and specializes in Internal Medicine. Dr. Tyler is affiliated with Providence Saint Johns Health Center.