Virginia Pediatric Eye Center 880 Kempsville Rd Suite 2500, Norfolk, VA 23502 7574610050 (Phone)
Certifications:
Ophthalmology, 2005
Awards:
Healthgrades Honor Roll
Languages:
English Spanish
Education:
Medical School Virginia Commonwealth University School Of Medicine Graduated: 1969 Medical School Greenville Hospital Sys Greenville Hospital Graduated: 2000 Medical School University Hosps Mc Va Graduated: 1970 Medical School Geisinger Med Center Geisinger Hospital Graduated: 2003 Medical School Ill Ee Infirm Graduated: 1975 Medical School Chldns National Med Center Graduated: 2004 Medical School National Med Center Chldns Hospital Graduated: 1976
Patricia B. Williams - Norfolk VA Earl R. Crouch - Virginia Beach VA
Assignee:
Center for Innovative Technology - Herndon VA
International Classification:
A61K 31195
US Classification:
514561
Abstract:
Persistent epithelial defects are effectively treated by topically applying a gelatinous composition containing either aminocaproic acid or tranexamic acid to the eye. In vivo results demonstrate improved healing of the epithelium and basement membrane complex. The gelatinous composition is prepared by a process that ensures sterility and proper pH conditions throughout the gel.
Topical Gel Containing Aminocaproic Acid Applied To The Eye
Patricia B. Williams - Norfolk VA Earl R. Crouch - Virginia Beach VA
Assignee:
The Center for Innovative Technology - Herndon VA Eastern Virginia Medical School - Norfolk VA
International Classification:
A61K 31195 A61K 9127
US Classification:
424427
Abstract:
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrhage and none have experienced adverse side effects. The topical gel formulation is prepared by a process which ensures sterility, a pH compatible with conditions in the aqueous humor, and optimum consistency. A permeation enhancer such as proparacaine can be incorporated into the gel during formulation and be used to enhance the transport of aminocaproic acid across the corneal epithelium.
Topical Containing Aminocaproic Acid For Preventing Secondary Hemorrhage Following Hyphema
Patricia B. Williams - Norfolk VA Earl R. Crouch - Virginia Beach VA
Assignee:
The Center for Innovative Technology - Herndon VA Eastern Virginia Medical School - Norfolk VA
International Classification:
A61K 31195 A61K 9127
US Classification:
424427
Abstract:
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrhage and none have experienced adverse side effects. The topical gel formulation is prepared by a process which ensures sterility, a pH compatible with conditions in the aqueous humor, and optimum consistency. A permeation enhancer such as proparacaine can be incorporated into the gel during formulation and be used to enhance the transport of aminocaproic acid across the corneal epithelium.
Method For Preparing A Topical, Aminocaproic Acid Containing Ophthalmic Gel
Patricia B. Williams - Norfolk VA Earl R. Crouch - Virginia Beach VA
Assignee:
Eastern Virginia Medical School - Norfolk VA The Center for Innovative Technology - Herndon VA
International Classification:
A61K 31195
US Classification:
424427
Abstract:
A topical gel formulation containing aminocaproic acid prevents secondary hemorrhage following hyphema without the adverse side effects associated with systemically delivered aminocaproic acid. Of ten human patients treated with the formulation, none have experienced a secondary hemorrhage and none have experienced adverse side effects. The topical gel formulation is prepared by a process which ensures sterility, a pH compatible with conditions in the aqueous humor, and optimum consistency. A permeation enhancer such as proparacaine can be incorporated into the gel during formulation and be used to enhance the transport of aminocaproic acid across the corneal epithelium.
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