Edward R Delaney

US Patent:

8470983, Jun 25, 2013

Filed:

Jun 3, 2010

Appl. No.:

12/793518

Inventors:

Edward Delaney - Princeton NJ, US
Mohammad Rahman - Lynchburg VA, US
Michael Caswell - Lynchburg NJ, US

Assignee:

Aptalis Pharma Canada Inc. - Mont-Saint-Hilaire

International Classification:

C07H 1/00
A61K 31/70

US Classification:

536 111, 536124, 514 23

Abstract:

Disclosed is L-glucose monohydrate and compositions thereof. Also disclosed are methods for making L-glucose monohydrate and compositions thereof. Further disclosed are methods for colonic cleansing using L-sugars, such as L-glucose monohydrate, and compositions and kits useful for colonic cleansing.

US Patent:

8618067, Dec 31, 2013

Filed:

Jun 3, 2010

Appl. No.:

12/793512

Inventors:

Michael Caswell - Lynchburg NJ, US
Edward Delaney - Princeton NJ, US
Mohammad Rahman - Lynchburg VA, US

Assignee:

Aptalis Pharma US, Inc. - Bridgewater NJ

International Classification:

A61K 31/70
A61K 47/00
C07H 1/00

US Classification:

514 23, 514 12, 514892, 536124

Abstract:

Disclosed is L-glucose monohydrate and compositions thereof. Also disclosed are methods for making L-glucose monohydrate and compositions thereof. Further disclosed are methods for colonic cleansing using L-sugars, such as L-glucose monohydrate, and compositions and kits useful for colonic cleansing.

US Patent:

20100093652, Apr 15, 2010

Filed:

Oct 29, 2009

Appl. No.:

12/608345

Inventors:

Nicholas Spring - Jenkintown PA, US
Edward J. Delaney - Princeton NJ, US

Assignee:

Topaz Pharmaceuticals Inc. - Horsham PA

International Classification:

A61K 31/7048
A01N 43/14
A01P 1/00
A61P 33/00

US Classification:

514 32

Abstract:

A topical formulation that inhibits the growth of microorganisms comprises an effective amount of an insecticide dissolved in an oil phase comprising a water-miscible or water-soluble surface active agent, a suspending agent, and a non-ionic surfactant, and an aqueous phase comprising one or more preservatives, where the aqueous phase is buffered to a specific pH. The overall antimicrobial efficacy in an emulsion formulation can be enhanced by buffering the aqueous phase of the emulsion to a pH at which the preservative system inhibits growth for a wider variety of microorganism types in the formulation relative to the equivalent formulation in which the aqueous phase is not buffered.

US Patent:

63133083, Nov 6, 2001

Filed:

Mar 20, 2000

Appl. No.:

9/528819

Inventors:

Ambarish Singh - Bordentown NJ
Chien-Kuang Chen - Marlboro NJ
John A. Grosso - Princeton Jct NJ
Edward J. Delaney - Princeton NJ
Xuebao Wang - East Brunswick NJ
Richard P. Polniaszek - Dayton NJ
John K. Thottathil - Princeton NJ

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D26116
C07D41312

US Classification:

548235

Abstract:

Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates therof. The present invention also relates to the novel intermediates prepared by these methods. The biphenyl isoxazole sulfonamides prepared by the present methods are endothelin antagonists useful, inter alia, for the treatment of hypertension, congestive heart failure and male erectile dysfunction.