Edward Doherty

US Patent:

50026615, Mar 26, 1991

Filed:

Aug 25, 1989

Appl. No.:

7/398739

Inventors:

William L. Chick - Wellesley MA
Susan J. Sullivan - Newton MA
Kermit M. Borland - Worcester MA
John M. Harvey - Worcester MA
Thomas E. Muller - Concord MA
Karen E. Dunleavy - Billerica MA
Donald P. King - Haverhill MA
Edward J. Doherty - Waltham MA
Barry A. Solomon - Bedford MA
Amy L. Foley - Framingham MA

Assignee:

W. R. Grace & Co.-Conn. - Lexington MA

International Classification:

B01D 6306

US Classification:

210192

Abstract:

A device which serves as an artificial pancreas comprises a hollow fiber having an inner diameter of about 5 mm which is surrounded by islets of Langerhans enclosed in a housing. The islets are suspended in a semi-solid matrix which ensures desired distribution of the cells about the hollow fiber. The hollow fiber and suspended islets are enclosed in a housing which further aids the desired distribution of islets about the hollow fiber. The hollow fiber has a porosity which selectively allows passage of substances having a molecular weight of less than about 100,000 Daltons. The semi-solid matrix in which the islets are embedded and suspended is formed of an appropriate supporting material such as alginate or agar.

US Patent:

39795926, Sep 7, 1976

Filed:

Apr 17, 1975

Appl. No.:

5/569024

Inventors:

Edward J. Doherty - Halifax MA
David W. Morrison - Burlington MA

Assignee:

Raytheon Company - Lexington MA

International Classification:

G01T 116

US Classification:

250363S

Abstract:

A radiographic imaging system coupled to a movable table for repositioning subject matter at the conclusion of a scanning of an area of the subject matter. The imaging system is further coupled to a plural axis recording system in which a recording implement, such as a flashing light source, is driven in synchronism with a scanning motion of the imaging system along a recording medium such as a photographic film. Controller circuitry is coupled between the movable table, the imaging system and the recording system for synchronizing their respective operations and for selectably scaling the movement of a drive unit relative to the movement of the scanning. A large subject such as a complete human being may be scanned by repositioning the subject and the movable table at the conclusion of each of a sequence of area scans of the imaging system, and by scaling the output of the scanning system so that the successively scanned regions of the subject can be recorded upon a single standard size x-ray film plate.

US Patent:

41952278, Mar 25, 1980

Filed:

Jun 20, 1978

Appl. No.:

5/917356

Inventors:

Richard W. Carman - Foxboro MA
Edward J. Doherty - Halifax MA

Assignee:

Union Carbide Corporation - New York NY

International Classification:

G02B 500

US Classification:

250505

Abstract:

Scanning apparatus is provided for a movable array of highly focused collimators surrounding a scan field.

US Patent:

42130549, Jul 15, 1980

Filed:

Dec 30, 1977

Appl. No.:

5/866016

Inventors:

Edward J. Doherty - Halifax MA

Assignee:

Union Carbide Corporation - New York NY

International Classification:

G02B 500
G01T 120

US Classification:

250505

Abstract:

Scanning apparatus is provided for an array of highly focused collimators surrounding a scan field.

US Patent:

20170246281, Aug 31, 2017

Filed:

Feb 16, 2017

Appl. No.:

15/434781

Inventors:

- Cambridge MA, US
Edward J. Doherty - Mansfield MA, US
Mark Cartwright - West Newton MA, US
Des White - Boston MA, US
Alexander G. Stafford - Revere MA, US
Omar Abdel-Rahman Ali - Cambridge MA, US
Amanda Graveline - Boston MA, US
Donald E. Ingber - Boston MA, US
David J. Mooney - Sudbury MA, US
Benjamin Seiler - Boston MA, US

International Classification:

A61K 39/108
A61K 39/02

Abstract:

The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.