Edward F Dougherty

US Patent:

20080280777, Nov 13, 2008

Filed:

May 9, 2008

Appl. No.:

12/118352

Inventors:

Michael Bittner - Phoenix AZ, US
Edward R. Dougherty - College Station TX, US

Assignee:

Translational Genomics Research Institute - Phoenix AZ

International Classification:

C40B 30/04
C12Q 1/68
G06K 9/46
G06G 7/48

US Classification:

506 9, 435 6, 703 11, 382133

Abstract:

The present invention describes methods for carrying out experiments on living cells, including making measurements of the operation transcriptional regulatory processes and indicators of the kinds of processes operating in the cell in response to external stimuli. Image analysis allows for gathering data concerning the flow of information through a cell's genomic regulatory network as it is executing a programmatic change in its activities as a function of said stimuli. The method also allows collection of data of the results of the information-processing in the cell by observing the decisions the cell makes when modulating cellular process activities.

US Patent:

20100010797, Jan 14, 2010

Filed:

Jul 15, 2009

Appl. No.:

12/503787

Inventors:

Michael Bittner - Phoenix AZ, US
Edward R. Dougherty - College Station TX, US

Assignee:

Translational Genomics Research Institute - Phoenix AZ

International Classification:

G06G 7/48

US Classification:

703 11

Abstract:

The present invention describes methods for carrying out experiments on living cells, including making measurements of the operation transcriptional regulatory processes and indicators of the kinds of processes operating in the cell in response to external stimuli. Image analysis allows for gathering data concerning the flow of information through a cell's genomic regulatory network as it is executing a programmatic change in its activities as a function of said stimuli. The method also allows collection of data of the results of the information-processing in the cell by observing the decisions the cell makes when modulating cellular process activities.