Edwin L Moore

US Patent:

42749786, Jun 23, 1981

Filed:

Dec 7, 1979

Appl. No.:

6/101341

Inventors:

Edwin G. Moore - Libertyville IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

G01N 3348
C09K 300

US Classification:

252408

Abstract:

This invention encompasses a standard for determining glycosylated hemoglobin comprising a mixture of hemoglobin or methemoglobin and about 1% to 25% of the 2,4-dinitrophenyl derivative of hemoglobin or methemoglobin wherein a 2,4-dinitrophenyl group blocks the allosteric binding site of hemoglobin or methemoglobin.

US Patent:

42004357, Apr 29, 1980

Filed:

Dec 26, 1978

Appl. No.:

5/973368

Inventors:

Stephen D. Stroupe - Libertyville IL
Edwin G. Moore - Libertyville IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

G01N 3316
G01N 2100

US Classification:

23230B

Abstract:

A method for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.

US Patent:

42553857, Mar 10, 1981

Filed:

Oct 23, 1979

Appl. No.:

6/087367

Inventors:

Stephen D. Stroupe - Libertyville IL
Edwin G. Moore - Libertyville IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

G01N 3372

US Classification:

422 61

Abstract:

A method, reagent and test kit for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.

US Patent:

42605164, Apr 7, 1981

Filed:

Dec 7, 1979

Appl. No.:

6/101353

Inventors:

Edwin G. Moore - Libertyville IL

Assignee:

Abbott Laboratories - North Chicago IL

International Classification:

C09K 300
G01N 3348

US Classification:

252408

Abstract:

This invention encompasses a standard for determining glycosylated hemoglobin comprising a mixture of hemoglobin or methemoglobin and about 1% to 25% of the N-[5-nitrotropon-2-yl] hemoglobin or methemoglobin derivative wherein the allosteric binding site is blocked.

US Patent:

54826888, Jan 9, 1996

Filed:

Feb 7, 1994

Appl. No.:

8/193380

Inventors:

Michael A. Vest - Oak Park IL
Samuel D. Fink - Aiken SC
David G. Karraker - Aiken SC
Edwin N. Moore - Aiken SC
H. Perry Holcomb - North Augusta SC

Assignee:

The United States of America as represented by the United States
Department of Energy - Washington DC

International Classification:

B01F 100

US Classification:

423 20

Abstract:

A two-step process for dissolving plutonium metal, which two steps can be carried out sequentially or simultaneously. Plutonium metal is exposed to a first mixture containing approximately 1. 0M-1. 67M sulfamic acid and 0. 0025M-0. 1M fluoride, the mixture having been heated to a temperature between 45. degree. C. and 70. degree. C. The mixture will dissolve a first portion of the plutonium metal but leave a portion of the plutonium in an oxide residue. Then, a mineral acid and additional fluoride are added to dissolve the residue. Alteratively, nitric acid in a concentration between approximately 0. 05M and 0. 067M is added to the first mixture to dissolve the residue as it is produced. Hydrogen released during the dissolution process is diluted with nitrogen.