James Krause - Madision CT, US Dario Doller - Sparta NJ, US Elena Beretta - Groton CT, US Lavanya Rajachandran - Cheshire CT, US Robbin Brodbeck - Madison CT, US
International Classification:
A61K 31/496 A61P 1/00 G01N 33/15
US Classification:
424009200, 514252120
Abstract:
Compositions and methods are provided for weight management. The compositions generally comprise a MCHR antagonist, either in combination with a CB1 antagonist or formulated for coadministration with a CB1 antagonist. Certain methods involve coadministering a MCHR antagonist and a CB1 antagonist to a patient.
Methods For Preventing And Treating Obesity In Patients With Mc4 Receptor Mutations
Lavanya Rajachandran - Wallingford CT, US Elena Beretta - Groton CT, US James Krause - Madison CT, US
International Classification:
C12Q 1/68 A61K 31/405
US Classification:
514419000, 435006000
Abstract:
Methods are provided for treating health conditions associated with altered MC4 receptor activity with melanin concentrating hormone receptor antagonists. Such compounds may be used, for example, to treat or prevent obesity and/or overeating, and to reduce body mass index, in patients carrying one or more MC4 receptor mutations.
Pfizer Aug 2008 - Oct 2010
Associate Director
Pfizer Aug 2008 - Oct 2010
Director at Pfizer
Pfizer Apr 2004 - Aug 2008
Principal Scientist
Neurogen Corporation Jan 2002 - Apr 2004
Senior Scientist I and Ii
Education:
University of Florida 1999 - 2002
Università Degli Studi Di Milano
Università Degli Studi Di Parma