Eric R Irwin

US Patent:

7158832, Jan 2, 2007

Filed:

Sep 26, 2001

Appl. No.:

09/963777

Inventors:

Robert S. Kieval - Medina MN, US
Bruce J. Persson - New Brighton MN, US
David J. Serdar - Shorewood MN, US
Peter T. Keith - St. Paul MN, US
Eric D. Irwin - Minneapolis MN, US

Assignee:

CVRx, Inc. - Maple Grove MN

International Classification:

A61N 1/18

US Classification:

607 44

Abstract:

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohornonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably in the carotid sinus. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.

US Patent:

7389149, Jun 17, 2008

Filed:

Jun 27, 2005

Appl. No.:

11/168753

Inventors:

Martin A. Rossing - Coon Rapids MN, US
Stephen L. Bolea - Watertown MN, US
David W. Mayer - Bloomington MN, US
Aaron Hjelle - Champlin MN, US
Thomas P. Crowley - Lino Lakes MN, US
Eric D. Irwin - Minneapolis MN, US

Assignee:

CVRX, Inc. - Minneapolis MN

International Classification:

A61N 1/05

US Classification:

607116, 607118, 607126, 600377

Abstract:

Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

US Patent:

7499742, Mar 3, 2009

Filed:

Mar 27, 2003

Appl. No.:

10/402911

Inventors:

Stephen L. Bolea - Watertown MN, US
Robert S. Kieval - Medina MN, US
Bruce J. Persson - Albertville MN, US
David J. Serdar - Shorewood MN, US
Peter T. Keith - St. Paul MN, US
Eric D. Irwin - Minneapolis MN, US
Martin A. Rossing - Coon Rapids MN, US

Assignee:

CVRx, Inc. - Minneapolis MN

International Classification:

A61B 5/04
A61N 1/00

US Classification:

600372, 607 2, 607117

Abstract:

Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.

US Patent:

7835797, Nov 16, 2010

Filed:

Dec 4, 2007

Appl. No.:

11/950092

Inventors:

Martin A. Rossing - Coon Rapids MN, US
Eric Irwin - Minneapolis MN, US

Assignee:

CVRx, Inc. - Minneapolis MN

International Classification:

A61N 1/00

US Classification:

607 44

Abstract:

An apparatus and a system can chronically and automatically measure a physiologic parameter associated with the high pressure side of the vasculature and/or regulate blood pressure based upon the measured parameter. The apparatus may be made up of a transducer, a baroreflex activation device having one or more electrodes, and a lead having two or more conductors. The system can measure a physiologic parameter and selectively administer a therapy, such as, for example, electro-stimulation of baroreceptors, based upon the measurement. The transducer for measuring the physiologic parameter can be chronically implanted in the high-pressure side of the vasculature. The implantation method may include intravascularly positioning the transducer in the external carotid artery in such a way that the transducer is first introduced into the arterial vasculature through the superior thyroid artery.

US Patent:

8014874, Sep 6, 2011

Filed:

Aug 8, 2007

Appl. No.:

11/836047

Inventors:

Martin A. Rossing - Coon Rapids MN, US
Stephen L. Bolea - Watertown MN, US
David W. Mayer - Bloomington MN, US
Aaron Hjelle - Champlin MN, US
Thomas P. Crowley - Lino Lakes MN, US
Eric D. Irwin - Minneapolis MN, US

Assignee:

CVRx, Inc. - Minneapolis MN

International Classification:

A61N 1/05

US Classification:

607118, 607116

Abstract:

Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include structure or mechanisms for externally securing the electrode assembly to a body part. A first connection structure is located on the lead body proximal the electrodes to anchor the lead body to a first anchor location in the body that generally moves in concert with the body part. A second connection structure is located on the lead body proximal to the first connection structure to anchor the lead body to a second anchor location that is at least partially independent of movement of the body part. The first and second anchor location are offset by a distance that is less than a distance between the first and second connection structures to provide strain relief for the electrodes.

US Patent:

20060004417, Jan 5, 2006

Filed:

Jun 27, 2005

Appl. No.:

11/168231

Inventors:

Martin Rossing - Coon Rapids MN, US
Robert Kieval - Medina MN, US
Roy Martin - Maple Grove MN, US
David Serdar - Shorewood MN, US
Eric Irwin - Minneapolis MN, US

Assignee:

CVRx, Inc. - Maple Grove CA

International Classification:

A61N 1/18
A61F 7/00
A61K 9/22

US Classification:

607009000, 607017000, 600016000, 607096000, 604891100

Abstract:

Devices, systems and methods provide baroreflex activation to prevent, or at least reduce the likelihood of occurrence of, cardiac arrhythmias. Various embodiments may additionally or alternatively promote recovery from arrhythmias. In one embodiment, a device for preventing or reducing the likelihood of occurrence of arrhythmias includes one or more baroreflex activation devices, one or more sensors coupled to the baroreflex activation device(s), and a processor for processing information from the sensor and activating and/or modulation the baroreflex activation device. Sensors, such as electrocardiogram devices, generally sense factors indicative of a potential, ensuing arrhythmia.

US Patent:

20060074453, Apr 6, 2006

Filed:

Oct 4, 2004

Appl. No.:

10/958694

Inventors:

Robert Kieval - Medina MN, US
Martin Rossing - Coon Rapids MN, US
Eric Irwin - Minneapolis MN, US
John Brintnall - Bloomington MN, US

Assignee:

CVRx, Inc. - Maple Grove MN

International Classification:

A61N 1/362

US Classification:

607009000

Abstract:

A method for treating heart failure in a patient involves activating a baroreflex system of the patient with at least one baroreflex activation device and resynchronizing the patient's heart with a cardiac resynchronization device. Activating the baroreflex system and resynchronizing the heart may be performed simultaneously or sequentially, in various embodiments. In some embodiments, one or more patient conditions are sensed, and such condition(s) may be used for setting and/or modifying the baroreflex activation and/or heart resynchronization. A device for treating heart failure includes a baroreflex activation member coupled with a cardiac resynchronization member. Some embodiments further include one or more sensors and a processor. In some embodiments, the device is fully implantable.

US Patent:

20070106340, May 10, 2007

Filed:

Sep 27, 2006

Appl. No.:

11/535666

Inventors:

Stephen Bolea - Watertown MN, US
Robert Kieval - Medina MN, US
Bruce Persson - Dresser WI, US
David Serdar - Shorewood MN, US
Peter Keith - St. Paul MN, US
Eric Irwin - Minneapolis MN, US
Martin Rossing - Coon Rapids MN, US

Assignee:

CVRx, Inc. - Maple Grove MN

International Classification:

A61N 1/00

US Classification:

607044000

Abstract:

Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.