Eric David Schell

US Patent:

7374927, May 20, 2008

Filed:

May 3, 2005

Appl. No.:

11/121849

Inventors:

John F. Palma - San Ramon CA, US
Eric B. Schell - Mountain View CA, US
Alan J. Williams - Albany CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12M 1/34
C12M 3/00
C07H 21/04
C12Q 1/68

US Classification:

4352872, 435 911, 435 6, 536 231, 536 243

Abstract:

The invention provides arrays for analysis of compromised nucleic acid samples, for example, nucleic acids obtained from formalin fixed paraffin embedded samples and methods to analyzed these compromised samples. Arrays are disclosed in which the probe selection region used to select probes for the array is the 300 bases of the target MRNA that are immediately upstream of the start of the poly(A) tail of the mRNA. The probes selected for the array are more biased toward the 3′ end of the mRNA than other arrays that are currently available.

US Patent:

7901882, Mar 8, 2011

Filed:

Apr 2, 2007

Appl. No.:

11/695599

Inventors:

Yanxiang Cao - Mountain View CA, US
Shivani Nautiyal - Portola Valley CA, US
Charles G. Miyada - San Jose CA, US
Christopher Davies - Walnut Creek CA, US
Gangwu Mei - Fremont CA, US
Alan J. Williams - Albany CA, US
Eric B. Schell - Mountain View CA, US
John E. Blume - Sunnyvale CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04

US Classification:

435 6, 536 231, 536 243

Abstract:

Arrays for genome-wide analysis of methylation are disclosed. In a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within CpG islands in samples from human, mouse and rat genomes.

US Patent:

20050136395, Jun 23, 2005

Filed:

May 10, 2004

Appl. No.:

10/843527

Inventors:

Michael Mittmann - Palo Alto CA, US
Eric Schell - Mountain View CA, US

Assignee:

Affymetrix, INC - Santa Clara CA

International Classification:

C12Q001/70
C12Q001/68
C12P019/34

US Classification:

435005000, 435006000, 435091200

Abstract:

The invention provides arrays and probes for resequencing a SARS virus using an array of probes that are complementary to a SARS reference sequence and to each possible single nucleotide substitution of the reference sequence. Methods of identifying mutations in viral sequences and methods of characterizing viral isolates are also provided. The invention also provides high throughput methods to monitor epidemics and pandemics caused by pathogens such as viruses.

US Patent:

20110166037, Jul 7, 2011

Filed:

Jan 27, 2011

Appl. No.:

13/015370

Inventors:

Yanxiang Cao - Mountain View CA, US
Shivani Nautiyal - Portola Valley CA, US
Charles G. Miyada - San Jose CA, US
Christopher Davies - Walnut Creek CA, US
Gangwu Mei - Fremont CA, US
Alan J Williams - Albany CA, US
Eric B. Schell - Mountain View CA, US
John E. Blume - Sunnyvale CA, US

Assignee:

AFFYMETRIX, INC. - Santa Clara CA

International Classification:

C40B 30/04

US Classification:

506 9

Abstract:

Arrays for genome-wide analysis of methylation are disclosed. IN a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within cpG islands in samples from human, mouse and rat genomes.

US Patent:

20180251841, Sep 6, 2018

Filed:

Oct 24, 2017

Appl. No.:

15/792665

Inventors:

- Carlsbad CA, US
Shivani Nautiyal - Portola Valley CA, US
Charles G. Miyada - San Jose CA, US
Christopher Davies - Walnut Creek CA, US
Gangwu Mei - Fremont CA, US
Alan J. Williams - Albany CA, US
Eric B. Schell - Mountain View CA, US
John E. Blume - Sunnyvale CA, US

International Classification:

C12Q 1/6883
C12Q 1/6837

Abstract:

Arrays for genome-wide analysis of methylation are disclosed. In a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within CpG islands in samples from human, mouse and rat genomes.

US Patent:

20150038352, Feb 5, 2015

Filed:

Oct 2, 2013

Appl. No.:

14/044737

Inventors:

- SANTA CLARA CA, US
Shivani Nautiyal - Portola Valley CA, US
Charles G. Miyada - San Jose CA, US
Christopher Davies - Walnut Creek CA, US
Gangwu Mei - Fremont CA, US
Alan J. Williams - Albany CA, US
Eric B. Schell - Mountain View CA, US
Jonh E. Blume - Sunnyvale CA, US

Assignee:

AFFYMETRIX, INC. - SANTA CLARA CA

International Classification:

C12Q 1/68

US Classification:

506 9

Abstract:

Arrays for genome-wide analysis of methylation are disclosed. In a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within CpG islands in samples from human, mouse and rat genomes.