Determining the presence of cancerous or pre-cancerous cervical lesions from AGUS-diagnosed Pap smear cells by observing the distribution of MN/CA9 antigen expressed on atypical or normal cells and diagnosing (a) significant lesions when MN/CA9 antigen is observed on atypical cells, (b) low grade lesions when MN/CA9 antigen is absent from atypical cells but is present on normal endocervical cells, and (c) a benign condition when MN/CA9 antigen is absent from both atypical cells and normal endocervical cells.
Diagnostic Method Using Expression Of Mn/Ca9 Protein In Ascus Pap Smears
Shu-Yuan Liao - Anaheim CA Eric J. Stanbridge - Corona del Mar CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G01N 33574
US Classification:
435 723, 435 71, 435 72, 424 64, 5303871
Abstract:
Determining the presence of cancerous or pre-cancerous cervical lesions from ASCUS-diagnosed Pap smear cells by observing the distribution of MN/CA9 antigen expressed on atypical or normal cells and diagnosing (a) significant lesions when MN/CA9 antigen is observed on atypical cells, (b) low grade lesions when MN/CA9 antigen is absent from atypical cells but is present on normal endocervical cells, and (c) a benign condition when MN/CA9 antigen is absent from both atypical cells and normal endocervical cells.
Systems And Methods For Efficient Collection Of Single Cells And Colonies Of Cells And Fast Generation Of Stable Transfectants
Nancy Allbritton - Irvine CA, US Christopher E. Sims - Irvine CA, US Yuli Wang - Irvine CA, US Mark Bachman - Irvine CA, US Eric Stanbridge - Corona Del Mar CA, US
Assignee:
The Regents of the University of California - Oakland CA
A plate manufactured to enable samples of cells, micro-organisms, proteins, DNA, biomolecules and other biological media to be positioned at specific locations or sites on the plate for the purpose of performing addressable analyses on the samples. Preferably, some or all of the sites are built from a removable material or as pallets so that a subset of the samples of interest can be readily isolated from the plate for further processing or analysis. The plate can contain structures or chemical treatments that enhance or promote the attachment and/or function of the samples, and that promote or assist in their analyses. Use of the plate advantageously enables the selection and sorting of cells based on dynamic phenomena and the rapid establishment of stable tranfectants.
Detection Of Prokaryotic Organism By Dna Hybridization
Eric J. Stanbridge - Corona Del Mar CA Ulf Gobel - Freiberg, DE
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12Q 168 C07H 2104
US Classification:
435 6
Abstract:
Biological probes useful for detecting mycoplasmas or prokaryotes in general, or specific mycoplasma and eubacterial species are derived from the ribosomal RNA gene by selecting particular nucleotide sequences common to the class of organisms being detected.
Eric J. Stanbridge - Corona del Mar CA Ulf B. Gobel - Berlin, DE
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12Q 108 C12N 1511 C07H 2104
US Classification:
435 6
Abstract:
Biological probes useful for detecting mycoplasmas or prokaryotes in general, or specific mycoplasma and eubacterial species are derived from the ribosomal RNA gene by selecting particular nucleotide sequences common to the class of organisms being detected.
Growth Factors, Tumor Promoters, and Cancer Genes: Proceedings of a Triton Biosciences-UCLA Symposium Held in Steamboat Springs, Colorado, April 6-13, 1986