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Aza-Bridged Bicyclic Amine Derivatives For Use As Novel Cholinergic Receptor Ligands
Harold Kohn - Chapel Hill NC, US T. Harden - Carrboro NC, US Myoung Kim - Chapel Hill NC, US Erik Bodor - Durham NC, US
International Classification:
C07D453/02
US Classification:
514/305000, 546/133000
Abstract:
The present invention discloses novel cholinergic receptor ligands. The present invention also relates to the synthesis of substituted derivatives of aza-bridged bicyclic amines for use as muscarinic receptor ligands as well as methods of regulating function of certain cholinergic receptors, and hence acting as antagonists, agonists and partial agonists at certain specific cholinergic receptor subtypes. The present invention also relates to methods for treating disorders associated with cholinergic receptors.
Aza-Bridged Bicyclic Amine Derivatives For Use As Novel Cholinergic Receptor Ligands
Harold Kohn - Chapel Hill NC, US T. Harden - Carrboro NC, US Myoung Kim - Chapel Hill NC, US Erik Bodor - Durham NC, US
International Classification:
C07D451/02 A61K031/46
US Classification:
514304000, 546125000, 546124000
Abstract:
The present invention discloses novel cholinergic receptor ligands. The present invention also relates to the synthesis of substituted derivatives of aza-bridged bicyclic amines for use as muscarinic receptor ligands as well as methods of regulating function of certain cholinergic receptors, and hence acting as antagonists, agonists and partial agonists at certain specific cholinergic receptor subtypes. The present invention also relates to methods for treating disorders associated with cholinergic receptors.
Lung-Targeted Corticosteroid Treatment In Viral Respiratory Disease, Covid-19 And Ards (Acute Respiratory Distress Syndrome)
Provided herein are methods for treating, preventing, minimizing and/or substantially inhibiting inflammation associated with a respiratory virus such as COVID-19 and/or acute respiratory distress syndrome (ARDS), comprising administering to the lungs of a subject, by inhalation, a composition comprising an effective amount of an active agent such as a corticosteroid (for example, loteprednol etabonate (LE)). Also provided are pharmaceutical compositions comprising an active agent, such as a corticosteroid (for example, loteprednol etabonate (LE)) in an amount effective to treat, minimize and/or substantially inhibit inflammation associated with the respiratory virus, such as COVID-19 and/or ARDS.
Brain Health Project
Chief Financial Officer
Cognifem Feb 2011 - Feb 2018
Vice President Finance, Chief Financial Officer
Bodor Laboratories Feb 2011 - Feb 2018
Vice President Research, Chief Financial Officer
Columbia Technology Ventures Jun 2008 - Jul 2009
Stv Fellow
University of Heidelberg Aug 2005 - Sep 2007
Humboldt Research Fellow
Education:
Columbia Business School 2008 - 2009
Master of Business Administration, Masters, Healthcare
University of North Carolina at Chapel Hill 1997 - 2005
Doctorates, Doctor of Philosophy, Pharmacology
Emory University 1992 - 1996
Bachelors, Bachelor of Science, Anthropology, Biology, Chemistry
Skills:
Biotechnology Lifesciences Protein Chemistry Drug Discovery Life Sciences Pharmaceutical Industry Cell Biology Cell Culture Clinical Development Molecular Biology Research Purification Pharmacology Protein Expression Drug Development In Vivo Assay Development Antibodies Biochemistry In Vitro Immunology Neuroscience Pharmaceuticals
Name / Title
Company / Classification
Phones & Addresses
Erik T. Bodor Director
Bodor Family Foundation, Inc Civic/Social Association
10225 Collins Ave, Miami, FL 33154
Erik T. Bodor Treasurer, Director, Vice President
Rodob Drug Research Inc Commercial Physical Research
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