Erik D Robinson

US Patent:

20100305309, Dec 2, 2010

Filed:

May 28, 2010

Appl. No.:

12/789966

Inventors:

Dean Ho - Chicago IL, US
Mark Chen - Chicago IL, US
Erik Pierstorff - Falls Church VA, US
Erik Robinson - Chicago IL, US
Robert Lam - Evanston IL, US
Rafael Shimkunas - Palo Alto CA, US
Xueqing Zhang - Evanston IL, US

Assignee:

Northwestern University - Evanston IL

International Classification:

C07K 17/14
C07H 21/00
C07C 237/26

US Classification:

530402, 536 221, 552203, 977773

Abstract:

The present invention provides various functionalized nanodiamond particles. In particular, the present invention provides soluble complexes of nanodiamond particles and therapeutic agents, for example insoluble therapeutics, anthracycline and/or tetracycline compounds, nucleic acids, proteins, etc.

US Patent:

20100040672, Feb 18, 2010

Filed:

Jun 9, 2009

Appl. No.:

12/481400

Inventors:

Dean Ho - Chicago IL, US
Robert Lam - Evanston IL, US
Mark Chen - Chicago IL, US
Houjin Huang - Evanston IL, US
Erik Pierstorff - Highland Park IL, US
Erik Robinson - Chicago IL, US

Assignee:

Northwestern University - Evanston IL

International Classification:

A61K 9/70
A61K 31/56
A61K 31/351

US Classification:

424443, 514179, 514459

Abstract:

The present invention provides materials and devices for the controlled release of therapeutics, and methods for uses thereof.

US Patent:

20160058887, Mar 3, 2016

Filed:

Jul 13, 2015

Appl. No.:

14/797722

Inventors:

- Evanston IL, US
Mark Chen - Chicago IL, US
Erik Pierstorff - Falls Church VA, US
Erik Robinson - Chicago IL, US
Robert Lam - Evanston IL, US
Rafael Shimkunas - Palo Alto CA, US
Xueqing Zhang - Evanston IL, US
Houjin Huang - Evanston IL, US

International Classification:

A61K 47/48
A61K 47/02
A61K 31/704

Abstract:

The present invention provides various functionalized nanodiamond particles. In particular, the present invention provides soluble complexes of nanodiamond particles and therapeutic agents, for example insoluble therapeutics, anthracycline and/or tetracycline compounds, nucleic acids, proteins, etc. The present invention also provides materials and devices for the controlled release of therapeutics, and methods for uses thereof.

US Patent:

20140348895, Nov 27, 2014

Filed:

May 21, 2014

Appl. No.:

14/283819

Inventors:

- Evanston IL, US
Erik M. Robinson - Chicago IL, US
Sunjay Kaushal - Pikesville MD, US
Patrick M. McCarthy - Winnetka IL, US

Assignee:

Northwestern University - Evanston IL

International Classification:

A61K 9/70

US Classification:

424423

Abstract:

The present invention provides single sheet and compound para-xylene films for therapeutic uses. For example, the present invention provides single sheet para-xylene films useful as tissue separators and/or adhesion barriers in a subject, where the top and/or bottom surfaces of such films have a water contact angle between 75 and 95 degrees (e.g., to prevent adhesion formation). The present invention also provides compound films composed of at least two para-xylene polymer films with a therapeutic molecule layer in between. Such compound films, when used in vivo (e.g., as a tissue separator and to treat inflammation or atrial fibrillation) allow either therapeutic molecule elution through one of the para-xylene layers, or therapeutic molecule release when the compound film is pierced, such as when it is sutured in place.