Erik D Spoerke

US Patent:

7534761, May 19, 2009

Filed:

Aug 21, 2003

Appl. No.:

10/645304

Inventors:

Samuel I. Stupp - Chicago IL, US
Erik D. Spoerke - Evanston IL, US
Shawn G. Anthony - New Stanton PA, US
Krista L. Niece - Evanston IL, US

Assignee:

North Western University - Evanston IL

International Classification:

A01N 37/18
A61K 38/00

US Classification:

514 2, 977795

Abstract:

The present invention provides a system of self-assembling peptide amphiphiles with an absolute net charge of 3 or greater whose design and function may be patterned after proteins involved in vertebrate mineralization or other tissue forming processes. This molecular system preferably consists of a hydrophobic hydrocarbon tail attached to a relatively hydrophilic peptide sequence. Self-assembly of this peptide amphiphile may be induced through pH variation, divalent ion addition, or dehydration. Variations of structural peptide sequences in the peptide amphiphile may enable the assembled nanofibers to be reversibly cross-linked for more or less structural stability, or may allow for control of the rate of self-assembly.

US Patent:

20040258726, Dec 23, 2004

Filed:

Feb 11, 2004

Appl. No.:

10/777030

Inventors:

Samuel Stupp - Chicago IL, US
Erik Spoerke - Albuquerque NM, US
Shawn Anthony - New Stanton PA, US
Krista Niece - Evanston IL, US

International Classification:

A61F002/00

US Classification:

424/423000, 424/093700

Abstract:

Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon.

US Patent:

20120100571, Apr 26, 2012

Filed:

Dec 21, 2007

Appl. No.:

11/962981

Inventors:

Samuel I. Stupp - Chicago IL, US
Erik D. Spoerke - Albuquerque NM, US
Shawn G. Anthony - New Stanton PA, US
Krista L. Niece - Evanston IL, US

Assignee:

NORTHWESTERN UNIVERSITY - Evanston IL

International Classification:

C12N 5/071
A61L 27/00
C12P 1/00
B82Y 5/00

US Classification:

435 41, 435402, 427 224, 977795, 977923

Abstract:

Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon.

US Patent:

20210320321, Oct 14, 2021

Filed:

Jan 20, 2021

Appl. No.:

17/153607

Inventors:

- Albuquerque NM, US
Erik David Spoerke - Albuquerque NM, US
Harlan James Brown-Shaklee - Albbuquerque NM, US
Leo J. Small - Albuquerque NM, US

International Classification:

H01M 10/0562
C04B 35/447
C04B 35/626
C04B 35/645
H01M 10/054

Abstract:

A sodium-ion conducting NaSICON ceramic can be densified via the addition of a solvent to a NaSICON powder and subsequent pressing under high pressure and mild heat. Densification to 90% relative density can be achieved, providing a path toward low-temperature fabrication of Na-ion conductors.

US Patent:

20210292572, Sep 23, 2021

Filed:

Sep 23, 2020

Appl. No.:

17/029630

Inventors:

- Albuquerque NM, US
C. Garrett Campbell - Albuquerque NM, US
Mathias C. Celina - Albuquerque NM, US
Erik David Spoerke - Albuquerque NM, US
Eric John Schindelholz - Columbus OH, US

International Classification:

C09D 5/08
C09D 7/40
C09D 179/02
C09D 139/02
C09D 163/00
B05D 7/14
B05D 7/00
C23F 11/173

Abstract:

Nanocomposite anticorrosion coating can be achieved by depositing alternating, multilayers of a cross-linkable polymer and dispersed and aligned inorganic platelets followed by cross-linking of the cross-linkable polymer. The cross-linkable polymer can be an externally cross-linkable polymer that is cross-linked by diffusing a cross-linking agent into the deposited multilayer coating. Alternately, the cross-linkable polymer can be a functionalized cross-linkable polymer that is cross-linked by self-curing, thermal heat curing, or light (e.g., UV) following deposition of the multilayer coating.

US Patent:

20200189942, Jun 18, 2020

Filed:

Nov 21, 2019

Appl. No.:

16/691333

Inventors:

- Albuquerque NM, US
Erik David Spoerke - Albuquerque NM, US

International Classification:

C02F 1/469

Abstract:

An alternating current electrodialysis device that uses two synergistic energy efficiency-increasing improvements to a traditional electrodialysis system: (1) membranes which rectify ionic currents and (2) supercapacitor electrodes. Together these components enable alternating current electrodialysis, offering significantly decreased system complexity, improved energy efficiency, and increased systems lifetimes.

US Patent:

20200078736, Mar 12, 2020

Filed:

Sep 11, 2018

Appl. No.:

16/128081

Inventors:

- Albuquerque NM, US
Stephen Percival - Albuquerque NM, US
Erik David Spoerke - Albuquerque NM, US

International Classification:

B01D 61/44
C08J 5/22
C08J 3/24
B01J 43/00
B01D 61/46
B01D 69/02
B01D 69/12
B01D 71/60
B01D 71/40

Abstract:

Nanostructured polyelectrolyte bilayers deposited by Layer-by-Layer deposition on nanoporous membranes can be selectively crosslinked to modify the polyelectrolyte charge density and control ionic selectivity independent of ionic conductivity. For example, the polyelectrolyte bilayer can comprise a cationic polymer layer, such as poly(ethyleneimine), and an anionic polymer layer, such as poly(acrylic acid). Increasing the number of bilayers increases the cation selectivity when the poly(ethyleneimine) layer is crosslinked with glutaraldehyde. Crosslinking the membranes also increases the chemical and mechanical strength of the polyelectrolyte films. This controllable and inexpensive method can be used to create ion-selective and mechanically robust membranes on porous supports for a wide range of applications.

US Patent:

20180163309, Jun 14, 2018

Filed:

Dec 9, 2016

Appl. No.:

15/374775

Inventors:

- Albuquerque NM, US
Paul G. Clem - Albuquerque NM, US
Erik David Spoerke - Albuquerque NM, US

International Classification:

C23C 18/16
C23C 18/44
H01M 4/04

Abstract:

The invention provides an inexpensive, scalable process for coating materials with a film of a refractory metal. As an example, the immersion process can comprise the deposition of a sacrificial zinc coating which is galvanically displaced by the ether-mediated reduction of oxophilic WClto form a complex WOClfilm, and subsequently annealed to crystalline, metallic tungsten. The efficacy of this process was demonstrated on a carbon foam electrode, showing a 50% decrease in electrode resistance and significant gains in electrochemical performance. This process enables voltage efficiency gains for electrodes in batteries, redox flow batteries, and industrial processes where high conductivity and chemical stability are paramount.