Ernest E Lane

US Patent:

6334873, Jan 1, 2002

Filed:

Sep 28, 1998

Appl. No.:

09/161809

Inventors:

Ernest Lane - Huntington Beach CA
David Tompkins - Surrey, GB
David Hemsley - Hertz, GB

Assignee:

Autogenics - Scotland

International Classification:

A61F 224

US Classification:

623 214, 623 215

Abstract:

An apparatus and a method for constructing a heart valve prepared from autologous tissue. Three tissue leaflets are held in place with tissue anchors on a tissue mounting frame having an annular base and a plurality of commissure posts extending from the base. An elastomeric sheath rests gently on the tissue leaflets to prevent the leaflets from coming off of the anchor hooks and encloses the leaflets to form valve cusps. The leaflets touch each other on a coaptation line with an angle of approximately 65Â relative to the commissure post. The heart valves can be constructed intraoperatively in a short time, typically ten minutes. The low coaptation angle and the fact that the leaflets are held in place without being clamped between two unyielding members minimize stress on the tissue.

US Patent:

6371983, Apr 16, 2002

Filed:

Oct 3, 2000

Appl. No.:

09/678756

Inventors:

Ernest Lane - Huntington Beach CA 92646

International Classification:

A61F 224

US Classification:

623 214

Abstract:

A trileaflet biological prosthetic heart valve comprising a thin, rigid annular outer frame which supports three elastic, laminated spring inner frames which in turn provide consistent geometric form and structure for attachment of tissue leaflets.

US Patent:

6497713, Dec 24, 2002

Filed:

Apr 28, 2000

Appl. No.:

09/561119

Inventors:

David Tompkins - Walton-on-Thames, GB
Ernest Lane - Huntington Beach CA
David Hemsley - Rickmansworth, GB

Assignee:

Autogenics - Portola Valley CA

International Classification:

A61B 1732

US Classification:

606167

Abstract:

The present invention provides a tissue cutting device and a method for accurately cutting tissue into tissue leaflets for autologous tissue heart valves in a minimal amount of time. The device includes a flexible backing pad located between a rotatable rotary table and a puck which houses several sharpened blades. The tissue to be cut is located on the flexible backing pad adjacent to the blades. The rotary table includes a hemispherically shaped raised cutting bar on the upper surface. When the rotary table is rotated, the cutting bar pushes the tissue against the blades in the puck, cutting the tissue into the desired shape.

US Patent:

7201771, Apr 10, 2007

Filed:

Dec 26, 2002

Appl. No.:

10/331086

Inventors:

Ernest Lane - Huntington Beach CA, US

Assignee:

Arbor Surgical Technologies, Inc. - Irvine CA

International Classification:

A61F 2/24

US Classification:

623 214

Abstract:

A trileaflet biological prosthetic heart valve () comprising a thin, rigid annular outer frame () which supports three elastic, laminated spring inner frames () which in turn provide consistent geometric form and structure for attachment of tissue leaflets ().

US Patent:

7422603, Sep 9, 2008

Filed:

Mar 11, 2005

Appl. No.:

11/078673

Inventors:

Ernest Lane - Huntington Beach CA, US

Assignee:

Arbor Surgical Technologies, Inc. - Irvine CA

International Classification:

A61F 2/24

US Classification:

623 214

Abstract:

A trileaflet biological prosthetic heart valve () comprising a thin, rigid annular outer frame () which supports three elastic, laminated spring inner frames () which in turn provide consistent geometric form and structure for attachment of tissue leaflets ().

US Patent:

7513909, Apr 7, 2009

Filed:

Apr 10, 2006

Appl. No.:

11/279246

Inventors:

Ernest Lane - Huntington Beach CA, US
Shouyan Lee - Rancho Santa Margarita CA, US
Charles Huang - Villa Park CA, US

Assignee:

Arbor Surgical Technologies, Inc. - Irvine CA

International Classification:

A61F 2/24

US Classification:

623 24

Abstract:

A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e. g. , attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e. g. , using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

US Patent:

7717955, May 18, 2010

Filed:

Feb 28, 2005

Appl. No.:

11/069081

Inventors:

Ernest Lane - Huntington Beach CA, US
Michael J. Drews - Sacramento CA, US
Donnell W. Gurskis - Belmont CA, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61F 2/24

US Classification:

623 241, 623 214

Abstract:

A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.

US Patent:

7951197, May 31, 2011

Filed:

Apr 6, 2009

Appl. No.:

12/419059

Inventors:

Ernest Lane - Huntington Beach CA, US
Shouyan Lee - Rancho Santa Margarita CA, US
Charles Huang - Villa Park CA, US

Assignee:

Medtronic, Inc. - Minneapolis MN

International Classification:

A61F 2/24

US Classification:

623 24

Abstract:

A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e. g. , attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e. g. , using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.