Evelyn M Chai

US Patent:

20060147985, Jul 6, 2006

Filed:

Mar 7, 2006

Appl. No.:

11/369628

Inventors:

Anthony Barone - San Jose CA, US
Glenn McGall - Palo Alto CA, US
Evelyn Chai - Foster City CA, US
Nam Ngo - Campbell CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C40B 40/08
C12Q 1/68
C07H 21/04

US Classification:

435006000, 536025320

Abstract:

VLSIPS™ manufacturing processes are of increasing commercial importance. The present invention provides methods and compositions for monitoring the efficiency and quality of polymer synthesis in VLSIPS™ arrays. Methods for monitoring polymer synthesis in an array on a substrate are provided. Mono-isomeric labels for the labeling of synthetic polymer arrays are provided. Methods and compositions for post-synthetically labeling polymers in polymer arrays are also provided.

US Patent:

7026114, Apr 11, 2006

Filed:

Nov 30, 1995

Appl. No.:

08/574461

Inventors:

Anthony D. Barone - Santa Clara CA, US
Glenn H. Mc Gall - Mountain View CA, US
Evelyn Chai - Foster City CA, US
Nam Quoc Ngo - Campbell CA, US

Assignee:

Affymetrix, Inc. - Santa Clara CA

International Classification:

C12Q 1/68
G01N 33/543
A61K 38/00
C07H 21/04

US Classification:

435 6, 435 4, 4352871, 4352887, 435DIG 1, 435DIG 34, 435DIG 49, 436518, 530333, 530334, 530335, 536 243, 536 253, 536 2531, 536 2532

Abstract:

VLSIPS™ manufacturing processes are of increasing commercial importance. The present invention provides methods and compositions for monitoring the efficiency and quality of polymer synthesis in VLSIPS™ arrays. Methods for monitoring polymer synthesis in an array on a substrate are provided. Monoisomeric labels for the labeling of synthetic polymer arrays are provided. Methods and compositions for post-synthetically labeling polymers in polymer arrays are also provided.