Everett Webster

US Patent:

20220362373, Nov 17, 2022

Filed:

Mar 3, 2022

Appl. No.:

17/685717

Inventors:

- Walnut CA, US
Nikhil Dhar - Boston MA, US
Nikolai Eroshenko - Boston MA, US
Taylor Gill - Cambridge MA, US
Kemo Jammeh - Cambridge MA, US
Marianna Keaveney - Walpole MA, US
Justin Quinn - Malden MA, US
Hannu Rajaniemi - Point Richmond CA, US
Everett Webster - North Andover MA, US

International Classification:

A61K 39/215
C07K 14/47
C07K 14/31
C07K 14/165
C07K 14/11

Abstract:

Disclosed herein are fusion polypeptides comprising: (i) a fragment antigen comprising an epitope of a target protein antigen; and (ii) a complement binding polypeptide. The disclosure also provides fusion polynucleotides (e.g., mRNA) encoding the same. Also disclosed herein are methods of making and using the fusion polypeptides and fusion polynucleotides of the present disclosure.