Jiangfeng Zhu from Houston, TX, age 48

Increasing Bacterial Succinate Productivity
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US Patent:

20130203137, Aug 8, 2013
Filed:

May 3, 2011
Appl. No.:

13/696268
Inventors:

Ka-Yiu San - Houston TX, US
George N. Bennett - Houston TX, US
Grant J. Balzer - Houston TX, US
Jiangfeng Zhu - Houston TX, US
Chandresh Thakker - Houston TX, US
Ailen M. Sanchez - Foster City CA, US
Assignee:

WILLIAM MARSH RICE UNIVERSITY - Houston TX
International Classification:

C12P 7/46
C12N 15/70
US Classification:

435145, 43525233
Abstract:

Improved bacteria for making succinate and other 4 carbon dicarboxylates from the Krebs cycle have modifications to reduce acetate, lactate, EtOH and formate, as well as turn on the glyoxylate shunt, produce more NADH and overexpress In one embodiment, the bacteria are ΔadhEΔldhAΔiclRΔack-pta plus PYC and NAD-dependant FDH.

Increasing Nadph-Dependent Products
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US Patent:

20100009418, Jan 14, 2010
Filed:

Aug 29, 2007
Appl. No.:

12/439497
Inventors:

Ka-Yiu San - Houston TX, US
George Bennett - Houston TX, US
Henry Lin - Houston TX, US
Irene Martinez - Houston TX, US
Jiangfeng Zhu - Houston TX, US
Assignee:

Rice University - Houston TX
International Classification:

C12P 17/08
C12N 1/20
US Classification:

435124, 4352523
Abstract:

A method of increasing cellular NADPH levels by expressing one or more genes that encode an enzyme that causes the production of NADPH. The system is combined with other enzymes that require NADPH, thus improving the overall yield of the desired product.

Jiangfeng Zhu