Firoz D Antia from 103 Randlett Park, Newton, MA 02465, age 63, Phone: 9175305489

Stationary Phases And A Purification Process Using The Stationary Phases
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US Patent:

20070010655, Jan 11, 2007
Filed:

Sep 1, 2004
Appl. No.:

10/569155
Inventors:

Firoz Antia - RAHWAY NJ, US
Russell Boyd - Monroe NJ, US
Jimmy DaSilva - Oak Ridge, GB
Kent Golden - Fanwood NJ, US
Joseph NtiGyabaah - Somerset NJ, US
Christopher Welch - Cranbury NJ, US
International Classification:

A61K 38/11
C07K 7/16
US Classification:

530315000, 530359000
Abstract:

This invention relates to a novel stationary phase of Formula I and a method for purifying a peptide or lipopeptide in liquid chromatography using select stationary phases, including the stationary phases of Formula I to improve the resolution and/or productivity of the purification. This chromatographic method can be used for either an analytical or preparative scale purification.

Using Amines Or Amino Acids As Mobile Phase Modifiers In Chromatography
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US Patent:

7241866, Jul 10, 2007
Filed:

Oct 24, 2003
Appl. No.:

10/526301
Inventors:

Kent E. Goklen - Fanwood NJ, US
Joseph Nti-Gyabaah - Somerset NJ, US
Firoz D. Antia - Montclair NJ, US
Mary Ellen Dahlgren - Metuchen NJ, US
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

C07K 1/00
US Classification:

530350
Abstract:

This invention relates to the use of amine, amino acid and amino acid ester mobile modifiers in normal phase chromatography to improve the resolution and or productivity of peptide and lipopeptide purification. This chromatographic method can be sued for either analytical or preparative scale purification.

Convergent Liquid Phase Syntheses Of Oligonucleotides
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US Patent:

20220348602, Nov 3, 2022
Filed:

May 8, 2020
Appl. No.:

17/608802
Inventors:

- Cambridge MA, US
- Tokyo, JP
Firoz Antia - Cambridge MA, US
Yannick Fillon - Cambridge MA, US
Xuan Zhou - Cambridge MA, US
Wuming Yan - Cambridge MA, US
Hong Jiang - Cambridge MA, US
Hien Nguyen - Cambridge MA, US
Robert S. Gronke - Cambridge MA, US
Taisuke Ichimaru - Kawasaki, JP
Takuya Hamagaki - Kawasaki, JP
Daisuke Takahashi - Kawasaki, JP
International Classification:

C07H 1/02
C07H 21/02
Abstract:

The present disclosure describes a convergent liquid phase process for manufacturing oligonucleotides by coupling two or more oligonucleotide fragments, each of which have two or more nucleotides. Also provided by the present disclosure are reaction steps involved the convergent liquid phase process.

Firoz D Antia