The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided.
Forrest H. Anthony - Villanova PA, US Edwin J. Thomas - Moorestown NJ, US Matthew Parris - Plainsboro NJ, US
Assignee:
Eleison Pharmaceuticals LLC - Princeton NJ
International Classification:
A61K 31/7028 A61K 31/7042 A61P 35/00 A61K 31/7034
US Classification:
514 25
Abstract:
The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2 (SGLT2) to block the uptake of glucose in the proximal tubules of the kidneys to decrease renal toxicity. The invention relates to the fields of biomedicine, pharmacology, and molecular biology.
Preventing Pulmonary Recurrence Of Cancer With Lipid-Complexed Cisplatin
Forrest H. Anthony - Villanova PA, US Matthew M. Parris - Plainsboro NJ, US Edwin J. Thomas - Moorestown NJ, US Guangtao Zhang - Princeton NJ, US
International Classification:
A61K 31/282 A61K 47/48
US Classification:
424450, 514492
Abstract:
The described invention provides methods for treating pulmonary cancer in a subject, by administering to the subject by inhalation a composition of inhalational lipid cisplatin (ILC) comprising a lipid-complexed cisplatin.
Nigel L. Webb - Bryn Mawr PA, US Matthews O. Bradley - Laytonsville MD, US Forrest Anthony - Villanova PA, US Mark Fisher - King of Prussia PA, US
Assignee:
Luitpold Pharmaceuticals, Inc., - Shirley NY
International Classification:
A61K 31/337 C07D 305/14
US Classification:
514449, 549510, 549511
Abstract:
The invention provides conjugates of fatty acids and anticancer agents useful in treating cancer, and compositions and formulations thereof. Methods for using the conjugates also are provided.
Boiling Springs High School Boiling Springs NC 1946-1950
Community:
Tarshish Stowe, Ruth Roberson, Tammy Rivers, Sarah Payne, Andre Reid, Jane Smith, Teresa Ketchie, Lanie Craven, Donald Mcintyre, James Miller, Kimberly Thompson