Francis A Fitzpatrick

US Patent:

41927990, Mar 11, 1980

Filed:

Sep 21, 1977

Appl. No.:

5/835352

Inventors:

Francis A. Fitzpatrick - Kalamazoo MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

A61K 3702
A61K 3900

US Classification:

260121

Abstract:

A method for the radioimmunoassay of PGE. sub. 1 -type and PGE. sub. 2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic. Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule. Antibodies are disclosed which are specific against PGE. sub. 1 -type and PGE. sub. 2 -type compounds, PGH. sub. 2, and PGX. Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.

US Patent:

43036716, Dec 1, 1981

Filed:

Jul 10, 1980

Appl. No.:

6/168846

Inventors:

Francis A. Fitzpatrick - Kalamazoo MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

A61K 3134

US Classification:

424285

Abstract:

The present invention provides novel formulations of prostacyclin suitable for parenteral administration and methods for making and using these formulations. These novel formulations include a pharmaceutically acceptable stabilizing concentration of albumin as a constituent thereof. Such novel formulations of prostacyclin are useful for its conventional pharmacological and therapeutical purposes, most to inhibition of blood platelet aggregation.

US Patent:

42184363, Aug 19, 1980

Filed:

Apr 26, 1979

Appl. No.:

6/033484

Inventors:

Francis A. Fitzpatrick - Kalamazoo MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

A61K 3702
A61K 3900

US Classification:

424 85

Abstract:

A method for the radioimmunoassay of PGE. sub. 1 -type and PGE. sub. 2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic. Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule. Antibodies are disclosed which are specific against PGE. sub. 1 -type and PGE. sub. 2 -type compounds, PGH. sub. 2, and PGX. Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.