Frank Byron Barnes

US Patent:

8406858, Mar 26, 2013

Filed:

May 1, 2006

Appl. No.:

11/913042

Inventors:

Priya N. Werahera - Aurora CO, US
John Daily - Lafayette CO, US
M. Scott Lucia - Larkspur CO, US
Adrie van Bokhoven - Denver CO, US
E. David Crawford - Denver CO, US
Frank Barnes - Boulder CO, US

Assignee:

The Regents of the University of Colorado, A Body Corporate - Denver CO

International Classification:

A61B 6/00

US Classification:

600476, 600407

Abstract:

Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation emission matrix is generated (). On-diagonal and off diagonal components of the excitation emission matrix are identified (). Spectroscopic measures are derived from the excitation emission matrix (), and are compared to a database of known spectra () permitting the tissue to be classified as benign or malignant (). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.

US Patent:

20130345544, Dec 26, 2013

Filed:

Nov 30, 2012

Appl. No.:

13/691067

Inventors:

The Regents of the University of Colorado - , US
John Daily - Lafayette CO, US
M. Scott Lucia - Larkspur CO, US
Adrie van Bokhoven - Denver CO, US
E. David Crawford - Denver CO, US
Frank Barnes - Boulder CO, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF COLORADO - Denver CO

International Classification:

A61B 5/00

US Classification:

600408, 600407, 600476, 600473

Abstract:

Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (). Spectroscopic measures are derived from the excitation-emission matrix (), and are compared to a database of known spectra () permitting the tissue to be classified as benign or malignant (). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.

US Patent:

57211949, Feb 24, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/480164

Inventors:

Robert M. Yandrofski - Littleton CO
John Charles Price - Boulder CO
Frank Barnes - Boulder CO
Allen M. Hermann - Golden CO
James Floyd Scott - Boulder CO

Assignee:

Superconducting Core Technologies, Inc. - Denver CO
University Research Corporation - Boulder CO

International Classification:

H01B 1202
H01G 706

US Classification:

505210

Abstract:

The present invention relates to a tuneable fringe effect capacitor for conducting radio frequency energy. The capacitor includes a thin film of ferroelectric material, a pair of films of a conductive material deposited on the ferroelectric film with a gap between the films, and a substrate for the ferroelectric material and the conductive films. The capacitance value across the gap is varied by applying a voltage to the ferroelectric material and thereby altering the dielectric constant of the ferroelectric material.

US Patent:

54729351, Dec 5, 1995

Filed:

Dec 1, 1992

Appl. No.:

7/983632

Inventors:

Robert M. Yandrofski - Littleton CO
John C. Price - Boulder CO
Frank Barnes - Boulder CO
Allen M. Hermann - Golden CO
James F. Scott - Boulder CO

International Classification:

H01P 118
H01P 900
H03H 1116
H01B 1202

US Classification:

505210

Abstract:

The disclosure relates to ferroelectric and superconducting thin films used in combination to produce low-loss passive microwave and millimeter wave devices which are frequency tuneable. Various metal oxide superconducting and ferroelectric thin films can be deposited in numerous multilayer geometries via a variety of deposition techniques to produce devices which can manipulate microwave and millimeter wave signals through the application of voltage bias signals across the ferroelectric films. Numerous superconducting microwave and millimeter wave devices, including delay lines, phase shifters, resonators, oscillators, filters, electrically-small antennas, half-loop antennas, directional couplers, patch antennas, and various radiative gratings, are made frequency-tuneable by utilizing voltage-tuneable capacitor structures fabricated from voltage-biased ferroelectric thin films. Tuneable antenna arrays are also disclosed incorporating the combined superconducting and ferroelectric thin film structures and geometries which allow for electrical steering of beam patterns by the application of one or more voltage bias signals to ferroelectric thin film gratings.

US Patent:

55898459, Dec 31, 1996

Filed:

Jun 7, 1995

Appl. No.:

8/484012

Inventors:

Robert M. Yandrofski - Littleton CO
John C. Price - Boulder CO
Frank Barnes - Boulder CO
Allen M. Hermann - Golden CO
James F. Scott - Boulder CO

Assignee:

Superconducting Core Technologies, Inc. - Golden CO

International Classification:

H01Q 1502

US Classification:

343909

Abstract:

The disclosure relates to ferroelectric and superconducting thin films used in combination to produce low-loss passive microwave and millimeter wave devices which are frequency tuneable. Various metal oxide superconducting and ferroelectric thin films can be deposited in numerous multilayer geometries via a variety of deposition techniques to produce devices which can manipulate microwave and millimeter wave signals through the application of voltage bias signals across the ferroelectric films. Numerous superconducting microwave and millimeter wave devices, including delay lines, phase shifters, resonators, oscillators, filters, electrically-small antennas, half-loop antennas, directional couplers, patch antennas, and various radiative gratings, are made frequency-tuneable by utilizing voltage-tuneable capacitor structures fabricated from voltage-biased ferroelectric thin films. Tuneable antenna arrays are also disclosed incorporating the combined superconducting and ferroelectric thin film structures and geometries which allow for electrical steering of beam patterns by the application of one or more voltage bias signals to ferroelectric thin film gratings.

US Patent:

20180360320, Dec 20, 2018

Filed:

Jul 16, 2018

Appl. No.:

16/036323

Inventors:

- Denver CO, US
John Daily - Lafayette CO, US
M. Scott Lucia - Larkspur CO, US
Adrie van Bokhoven - Denver CO, US
E. David Crawford - Denver CO, US
Frank Barnes - Boulder CO, US

International Classification:

A61B 5/00

Abstract:

Methods and systems for in vivo classification of tissue are disclosed. The tissue is irradiated with light from multiple light sources and light scattered and fluoresced from the tissue is received. Distinct emissions of the sample are identified from the received light. An excitation-emission matrix is generated (). On-diagonal and off-diagonal components of the excitation-emission matrix are identified (). Spectroscopic measures are derived from the excitation-emission matrix (), and are compared to a database of known spectra () permitting the tissue to be classified as benign or malignant (). An optical biopsy needle or an optical probe may be used to contemporaneously classify and sample tissue for pathological confirmation of diagnosis.