Norman R. Wainwright - Falmouth MA, US Foster T. Jordan - Chapin SC, US Frank C. Rumore - Lebanon NJ, US Charles Balas, Jr. - Madison CT, US
Assignee:
Charles River Laboratories, Inc. - Wilmington MA
International Classification:
C12M 1/34 C12M 3/00 C12Q 1/37
US Classification:
4352887, 435 23, 4352883, 4352884, 4352879
Abstract:
The invention provides methods and compositions for the detection and/or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the invention provides a test cartridge useful in the practice of hemocyte lysate-based assays for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides methods of making and using such cartridges. In addition, the invention provides a rapid, sensitive, multi-step kinetic hemocyte lysate-based assay for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides a glucan-specific lysate that can be used in a variety of assay formats, including, for example, a test cartridge, optionally configured to perform a kinetic assay.
Methods And Compositions For The Detection Of Microbial Contaminants
Norman Wainwright - Falmouth MA, US Foster Jordan - Chapin SC, US Frank Rumore - Lebanon NJ, US Charles Balas - Madison CT, US
International Classification:
C12Q 1/04
US Classification:
435034000
Abstract:
The invention provides methods and compositions for the detection and/or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the invention provides a test cartridge useful in the practice of hemocyte lysate-based assays for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides methods of making and using such cartridges. In addition, the invention provides a rapid, sensitive, multi-step kinetic hemocyte lysate-based assay for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides a glucan-specific lysate that can be used in a variety of assay formats, including, for example, a test cartridge, optionally configured to perform a kinetic assay.
Methods And Compositions For The Detection Of Microbial Contaminants
Norman R. Wainwright - Falmouth MA, US Foster T. Jordan - Chapin SC, US Frank C. Rumore - Lebanon NJ, US Charles Balas, JR. - Madison CT, US
International Classification:
C12Q 1/04
US Classification:
435 34
Abstract:
The invention provides methods and compositions for the detection and/or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the invention provides a test cartridge useful in the practice of hemocyte lysate-based assays for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides methods of making and using such cartridges. In addition, the invention provides a rapid, sensitive, multi-step kinetic hemocyte lysate-based assay for the detection and/or quantification of a microbial contaminant in a sample. In addition, the invention provides a glucan-specific lysate that can be used in a variety of assay formats, including, for example, a test cartridge, optionally configured to perform a kinetic assay.
Harvey F. Padden - Pompton Lakes NJ Frank C. Rumore - Mahwah NJ
Assignee:
Computer Control Corporation - Pompton Plains NJ
International Classification:
G01N 3502 B01L 314
US Classification:
7386321
Abstract:
A tube magazine for a sampling system has a plurality of sampler tube receiving spaces for receiving sampler tubes. The sampler tubes can be separated from the system as a unit, and transported to another location for analysis. A first part of the system includes a plurality of introducing devices disposed for introducing gaseous fluid into corresponding ones of the sampler tubes; and a second part which forms with the sampler tubes a replaceable magazine which is readily removable from the first part, whereby the corresponding introducing devices and receiving spaces are simultaneously brought into fluid communication when the first and second parts are connected together. Advantageously, each of the sampler tube receiving spaces has a central, elongated axis, the axes of the sampler tube receiving spaces being parallel to each other; a trap tube receiving space for receiving a trap tube, the trap tube receiving space being surrounded by the sampler tube receiving spaces, the trap tube receiving space having an elongated, central axis which is parallel to the axes of the sampler tube receiving spaces; and a common end space for providing fluid communication between the trap tube receiving space and each of the sampler tube receiving spaces. A selector valve system can be provided for selectively introducing fluid into the sampler tube receiving spaces.
Harvey F. Padden - Pompton Lakes NJ Frank C. Rumore - Mahwah NJ Scott R. Calvert - Hewitt NJ
Assignee:
Computer Control Corporation - Pompton Plains NJ
International Classification:
G01F 100
US Classification:
73253
Abstract:
The invention relates to a high accuracy flowmeter for testing and calibrating flowmeters and the like, and more particularly to a positive displacement flowmeter which may include a cylinder (12), a piston (10) within the cylinder (12) which makes a clearance seal with the inside of the cylinder, an encoder (40) associated with the piston, and a control valve (V) for controlling the supply of a fluid flow (A1) to be measured. More generally, the flowmeter includes a channel for receiving a fluid flow so as to move the piston (10) within its enclosure (12); and a device (36, 38, 40) for detecting movement of the piston and generating electrical signals representative of the fluid flow to be measured. The movement of the piston is detected as a function of a known volume of the enclosure traversed by the piston, and a measured variable elapsed time over which the piston traverses the volume. Preferably, the flowmeter system includes a damping device (FIGS.
Harvey F. Padden - Pompton Lakes NJ Frank C. Rumore - Mahwah NJ Scott R. Calvert - Hewitt NJ
Assignee:
Computer Control Corp. - Pompton Plains NJ
International Classification:
G01M 1900
US Classification:
73239
Abstract:
A high accuracy flowmeter for testing and calibrating flowmeters and the like, and more particularly a positive displacement flowmeter which may include a cylinder (12), a piston (10) within the cylinder (12) which makes a clearance seal with the inside of the cylinder, an encoder (40) associated with the piston, and a control valve (V) for controlling the supply of a fluid flow (A1) to be measured. The flowmeter may have an arrangement for receiving differently-sized interchangeable modules for measurement of different flow rate ranges, each module having for example a compatible piston and cylinder of a predetermined size. The flowmeter includes a channel for receiving a fluid flow so as to move the piston (10) within its cylinder (12); and a device (36, 38) including the encoder (40) for detecting movement of the piston and generating electrical signals representative of the fluid flow to be measured. The movement of the piston is detected as a function of a known volume of the enclosure traversed by the piston, and a measured variable elapsed time over which the piston traverses the volume. Preferably, the flowmeter system includes a damping device (FIGS.
- Somerset NJ, US Haiguang Lu - Los Altos CA, US Alla Shtabnaya - Hillsborough NJ, US Frank Rumore - Flemington NJ, US Patrick Anderson - Woodstock MD, US
Assignee:
Go!Foton Holdings, Inc. - Somerset NJ
International Classification:
G02B 6/44 G02B 6/38 H04Q 1/02 H04Q 1/06
Abstract:
A communication system may include a first chassis having first and second side walls and adapted to slidably receive therein a plurality of cassettes. A first cable hanger assembly may have a first side edge hingedly coupled to the first side wall of the first chassis, the first cable hanger assembly including a plurality of first hangers adapted to support cables thereon. An axis of rotation of the first cable hanger assembly may be substantially orthogonal to a direction in which the plurality of cassettes are slideable. The cable hanger assembly may be rotatable from a first position to a second position so that during rotation from the first position to the second position, the plurality of first hangers move toward front faces of the plurality of cassettes.
Name / Title
Company / Classification
Phones & Addresses
Frank Rumore Owner
Peter Frank Salon & Colour Grp Beauty Salons
197 N Long Bch Rd, Rockville Centre, NY 11570 5166780023, 5166787481
Frank Rumore Principal
Princeton Tech Sciences Business Services at Non-Commercial Site
Princeton Technical Sciences since Jan 2007
CTO
Cambridge Instruments Jul 2001 - Dec 2006
Technology Director
International Technidyne Coporation Aug 1993 - Jun 2001
Principal Engineer
BIOS International Oct 1989 - Jul 1993
Product Development Engineer
Becton Dickinson Apr 1988 - Oct 1989
Senior Product Development Engineer
Education:
Massachusetts Institute of Technology 1974 - 1976
The Cooper Union for the Advancement of Science and Art 1970 - 1974
Skills:
Rapid Prototyping R&D Biomedical Engineering Medical Devices Prototyping Product Development Product Launch Manufacturing Design Control Systems Engineering Labview Machine Design Machining Sensors Software Development
Princeton Technical Sciences
Chief Technology Officer
Cambridge Instruments Jul 2001 - Dec 2006
Technology Director
International Technidyne Corporation Aug 1993 - Jun 2001
Principal Engineer
Bios International Corp. Oct 1989 - Jul 1993
Product Development Engineer
Bd Apr 1988 - Oct 1989
Senior Product Development Engineer
Education:
Massachusetts Institute of Technology 1974 - 1976
Master of Science, Masters, Mechanical Engineering
The Cooper Union For the Advancement of Science and Art 1970 - 1974
Bachelors, Bachelor of Science, Mechanical Engineering
Skills:
Cross Functional Team Leadership Manufacturing Medical Devices R&D Product Development Testing Engineering Management Sensors Design of Experiments Rapid Prototyping Biomedical Engineering Prototyping Product Launch Design Control Machine Design Machining Software Development Labview Systems Engineering Biotechnology Iso 13485 Fda Engineering Project Management Mechanical Engineering Laboratory Management Six Sigma Research and Development
2007 to 2000 Chief Technical OfficerCambridge Instruments, LLC Madison, CT Jul 2001 to Dec 2009 Technology DirectorInternational Technidyne Corporation Edison, NJ 1993 to 2001 Principal EngineerComputer Control Corporation Pompton Plains, NJ 1989 to 1993 Senior Development EngineerBecton-Dickinson, Criti-Chem Products Group Fair Lawn, NJ 1988 to 1989 Senior Development EngineerAerco International, Inc Northvale, NJ 1985 to 1988 Senior Development EngineerGilian Instrument Corporation Wayne, NJ 1983 to 1985 Director of Research and DevelopmentElectro-Nucleonics/Pharmacia Fairfield, NJ 1979 to 1983 Mechanical EngineerMassachusetts Institute of Technology Cambridge, MA 1976 to 1979 Cryogenic Electro-Mechanical Engineer
Education:
Massachusetts Institute of Technology Cambridge, MA 1974 to 1976 Master of Science in Electro-Mechanical EngineeringCooper Union New York, NY 1970 to 1974 Bachelor of Science in Mechanical Engineering
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