Franklin D Johnson

US Patent:

20090196890, Aug 6, 2009

Filed:

Dec 17, 2008

Appl. No.:

12/337052

Inventors:

Alfred Liang - Edison NJ, US
Franklin Johnson - Bridgewater NJ, US
Xiaohong Qi - Whitehouse Station NJ, US

Assignee:

Alpharma Pharmaceuticals, LLC - Bridgewater NJ

International Classification:

A61K 9/00
A61K 31/34

US Classification:

424400, 514468

Abstract:

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated.

US Patent:

20220313670, Oct 6, 2022

Filed:

Jun 11, 2020

Appl. No.:

17/618277

Inventors:

- Philadelphia PA, US
Franklin Johnson - Bridgewater NJ, US

Assignee:

Amicus Therapeutics, Inc. - Philadelphia PA

International Classification:

A61K 31/445

Abstract:

Provided are methods for treatment of Fabry disease in a patient having renal impairment. Certain methods comprise administering to the patient about 100 mg to about 300 mg free base equivalent of migalastat or salt thereof at a frequency of greater than once every other day, such as once every four or seven days. Certain methods comprise measuring lyso-Gb3 and/or migalastat in one or more plasma samples from the patient.

US Patent:

20160354364, Dec 8, 2016

Filed:

Aug 22, 2016

Appl. No.:

15/242780

Inventors:

- Bridgewater NJ, US
Franklin Johnson - Bridgewater NJ, US
Xiaohong Qi - Whitehouse Station NJ, US

International Classification:

A61K 31/485
A61K 9/16
A61K 9/50

Abstract:

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated.

US Patent:

20150297527, Oct 22, 2015

Filed:

Jan 15, 2015

Appl. No.:

14/597552

Inventors:

- Bridgewater NJ, US
Franklin Johnson - Bridgewater NJ, US
Xiaohong Qi - Whitehouse Station NJ, US

International Classification:

A61K 9/48
A61K 9/16
A61K 31/485

Abstract:

Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided. Methods for treating pain using such compositions is also demonstrated.