Fred Samuel Greensite

US Patent:

49910922, Feb 5, 1991

Filed:

Aug 12, 1988

Appl. No.:

7/231830

Inventors:

Fred Greensite - Newport Beach CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G06F 1568

US Classification:

36441313

Abstract:

An imaging technique is disclosed for enhancing the contrast of an image, in particular for enhancing the contrast between subregions of a region of interest which may have similar signal characteristics and significantly distinct physical properties. A distribution density function describing the density of the signal in a signal space assigned to a voxel of the region to be imaged is first computed. This distribution function is then convolved with a resolution function, preferably a Gaussian function. Advantageously, the variance of the Gaussian is greater and a multiple of the variance of the noise statistics of the input image. The result of the convolution of the distribution function with the resolution function defines a scale, preferably a grey scale which assigns a particular tone to a pixel of the image corresponding to the voxel of the region to be imaged. The standard deviation is preferably chosen by the user and defines the resolution of the final image in the signal space. The noise in the output image can be decreased by increasing the standard deviation of the convolving Gaussian.

US Patent:

41215761, Oct 24, 1978

Filed:

Feb 9, 1977

Appl. No.:

5/766932

Inventors:

Fred Samuel Greensite - Del Mar CA

International Classification:

A61B 504

US Classification:

128 206V

Abstract:

Vector cardiogram signals are processed by an analog computer circuit during a QRS wave interval in which a sheet of depolarization traverses a heart muscle to provide signals which enable a determination of the relative volume of heart muscle tissue that is functioning during the QRS wave interval. By comparing such relative volumes determined from signals processed from vectorcardiograms produced both before and after an "intervention" affecting the heart muscle, such as either a myocardial infarction or a therapeutic intervention following a myocardial infarction, it is possible to make a quantitative determination of the percentage of heart muscle tissue affected by the intervention. A signal proportional to the volume of heart muscle tissue affected by a myocardial infarction is provided by processing vectorcardiogram signals obtained during a QRS wave interval prior to or at the onset of the infarction and vectorcardiogram signals obtained during a QRS wave interval following the infarction.