Biocompatible Synthetic And Collagen Compositions Having A Dual-Type Porosity For Treatment Of Wounds And Pressure Ulcers And Therapeutic Methods Thereof
Frederick H. Silver - Bangor PA Richard A. Berg - Lambertville NJ charles J. Doillon - Edison NJ Arkady Chernomorsky - Elizabeth NJ Robert M. Olson - Princeton NJ
Assignee:
University of Medicine and Dentistry of New Jersey - Newark NJ
International Classification:
C08F22032 A61K 39385 A61K 1500 G01N 3354
US Classification:
530356
Abstract:
A therapeutic method for treating pressure ulcers like decubitus ulcers with biodegradable collagen flake compositions and with biodegradable collagen sponge or sponge-like compositions. The products of the invention includes biodegradable collagen flake compositions and biodegradable collagen sponge or sponge-like compositions. The products are useful for medical applications, like skin reconstruction, treatment of wounds, especially deep wounds, also in connection with surgery, including cosmetic surgery. The invention also deals with biocompatible synthetic resin sponge or sponge-like and flake products for medical and similar applications. The invention contemplates the treatment of human and animal species.
Frederick H. Silver - Bangor PA David Christiansen - Somerville NJ
International Classification:
A61K 3712 C07K 1400 C08H 106 C08L 8900
US Classification:
530356
Abstract:
There is disclosed a process for the mineralization of collagen fibers whereby collagen fibers formed from collagen are contacted with a solution of calcium and phosphate ions under conditions to effect nucleation and in-vitro growth of mineral crystals within and on the surface of the collagen fibers to form intact collagen fibers with subfibrillar substructure and wherein preparations of such mineralized collagen fibers are used in bone replacement therapy as well as to induce repair in bony defects.
Process For The Mineralization Of Collagen Fibers, Product Produced Thereby And Use Thereof To Repair Bone
Frederick H. Silver - Bangor PA David Christiansen - Somerville NJ
International Classification:
A61K 3712 C07K 1400 C08H 106 C08L 8900
US Classification:
514 21
Abstract:
There is disclosed a process for the mineralization of collagen fibers whereby collagen fibers formed from collagen are contacted with a solution of calcium and phosphate ions under conditions to effect nucleation and in-vitro growth of mineral crystals within and on the surface of the collagen fibers to form intact collagen fibers with subfibrillar substructure and wherein preparations of such mineralized collagen fibers are used in bone replacement therapy as well as to induce repair in bony defects.
Method And Apparatus For Lidc Enhanced Wound Healing Using Biocompatible Tissue Ingrowth Implants
Frederick H. Silver - Bangor PA Michael G. Dunn - Aberdeen NJ
Assignee:
University of Medicine and Dentistry of New Jersey - Newark NJ
International Classification:
A61L 1501 C07K 1506 A61N 132
US Classification:
530356
Abstract:
A therapeutic method for treating wounds by dressing the wound with a biocompatible biodegradable collagen tissue product and applying Low Intensity Direct Current (LIDC) to the product. The devices of the invention include biocompatible biodegradable collagen tissue products having means for the application of LIDC to the dressed wound.
Process And Apparatus For Harvesting Tissue For Processing Tissue And Process And Apparatus For Re-Injecting Processed Tissue
Frederick H. Silver - Bangor PA Ary S. Chernomorsky - Morris Plains NJ
International Classification:
A61B 1700
US Classification:
604 28
Abstract:
There is disclosed a method and apparatus for harvesting tissue using a cannula having a diameter of from 0. 5 to 4. 0 mm and of a length of from 25 to 20 cm to access by minimally invasive techniques a host to withdraw autogenous tissue processed to remove loose fat and/or fragmented tissue. Thereafter, the resulting tissue substrate is morcellated to form particulate tissue of a particle size of from 1 to 200. mu. m. The particulate material is thence passed through screens having opening sizes of from 1 to 100. mu. m to form a material of a size for introduction into a syringe of from 16 to 30 gauge for implantation in the host. The processed tissue may be admixed with extenders, gelling agents and the like.
Synthetic Collagen Orthopaedic Structures Such As Grafts, Tendons And Other Structures
Frederick H. Silver - Bangor PA Yasushi P. Kato - Edison NJ
Assignee:
University of Medicine and Dentistry of New Jersey - Newark NJ
International Classification:
A61F 228 A61F 210 A61F 202
US Classification:
623 13
Abstract:
The invention provides graft, prothesis, orthopaedic structures, implants and like body replacement parts which are constituted of synthetic collagen fibers, an embodiment of which is a tendon or a ligament prosthesis, graft or implants. These body parts have a combination of very useful properties, particularly high tensile strength combined with biocompatability.
Isbn (Books And Publications)
Mechanosensing And Mechanochemical Transduction in Extracellular Matrix: Biological, Chemical, Engineering, And Physiological Aspects