Fu W Chen

US Patent:

6417268, Jul 9, 2002

Filed:

Dec 6, 1999

Appl. No.:

09/455024

Inventors:

Huashi T. Zhang - South Pasadena CA
Baraka A. Kawawa - Bensalem PA
Fu Chen - Newtown PA

Assignee:

Hercules Incorporated - Wilmington DE

International Classification:

C08L 3100

US Classification:

524833, 524 55, 524831, 524832

Abstract:

Method for producing an hydrophobically associative polymer is provided which is characterized by forming a monomer solution comprising a surfactant, at least one hydrophobic ethylenically unsaturated monomer, at least one hydrophilic monomer selected from nonionic ethylenically monomers, cationic ethylenically unsaturated monomers, anionic ethylenically unsaturated monomers or mixtures thereof, and water; forming a salt solution comprising a multivalent salt and water; mixing the monomer solution and salt solution to form a mixed solution; and charging the mixed solution with an initiator, thereby polymerizing the monomers to form the hydrophobically associative polymer in a dispersion. Aqueous dispersion containing the hydrophobically associative polymer formed by the method. The aqueous dispersion containing the hydrophobically associative polymer may be used in a paint formulation, in a mobility control fluid useful in enhanced oil recovery, in a secondary or tertiary oil recovery system, in an enhanced oil recovery method, in a cementious composition, in an oil well drilling mud formulation, in a fracturing fluid formulation, in a wastewater treatment system, or in a dewatering sludge system.

US Patent:

20070128118, Jun 7, 2007

Filed:

Dec 1, 2006

Appl. No.:

11/566141

Inventors:

Lei Yu - Carlsbad CA, US
Gang Zhao - Vista CA, US
Sang Van - San Diego CA, US
Sanjib Das - Oceanside CA, US
Zhongling Feng - San Diego CA, US
Xiaoli Fu - Vista CA, US
Xinghe Wang - San Diego CA, US
Yi Jin - Carlsbad CA, US
Fu Chen - Carlsbad CA, US

Assignee:

Nitto Denko Corporation - Osaka

International Classification:

A61K 49/10
A61K 49/00
A61K 31/785

US Classification:

424009322, 424009600, 424078270, 525054100

Abstract:

Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.

US Patent:

20080181852, Jul 31, 2008

Filed:

Jan 24, 2008

Appl. No.:

12/019612

Inventors:

Lei Yu - Carlsbad CA, US
Gang Zhao - Vista CA, US
Sang Van - San Diego CA, US
Sanjib Kumar Das - Oceanside CA, US
Fu Chen - Carlsbad CA, US
Yi Jin - Carlsbad CA, US
Xiaoli Fu - Vista CA, US

Assignee:

Nitto Denko Corporation - Osaka

International Classification:

A61K 31/337
A61K 47/30
A61K 31/435
A61K 31/70
A61K 49/12
A61P 35/00

US Classification:

424 936, 5147723, 514449, 514283, 514 34

Abstract:

Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.

US Patent:

20100028416, Feb 4, 2010

Filed:

Sep 12, 2008

Appl. No.:

12/210125

Inventors:

Lei Yu - Carlsbad CA, US
Gang Zhao - Vista CA, US
Sang Van - San Diego CA, US
Fu Chen - Carlsbad CA, US

Assignee:

Nitto Denko Corporation - Osaka

International Classification:

A61K 9/127
A61K 31/7088

US Classification:

424450, 514 44 R, 514 44 A, 424 783

Abstract:

Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.

US Patent:

20120107264, May 3, 2012

Filed:

Oct 13, 2011

Appl. No.:

13/273106

Inventors:

Padmanabh Chivukula - San Diego CA, US
Jian Liu - San Diego CA, US
Akinobu Soma - Carlsbad CA, US
Keisaku Okada - San Diego CA, US
Sang Van - San Diego CA, US
Julia Zhu - Escondido CA, US
Nianchun Ma - Oceanside CA, US
Chen-Chang Lee - Oceanside CA, US
Fu Chen - Carlsbad CA, US
Lei Yu - Carlsbad CA, US

Assignee:

Nitto Denko Corporation - Osaka

International Classification:

A61K 47/48
C08F 220/60
A61P 35/00
A61K 47/32
C12N 5/071
C08F 120/60
C08G 65/333

US Classification:

424 7827, 5253284, 525 542, 525421, 5147721, 435375

Abstract:

Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.

US Patent:

20120189554, Jul 26, 2012

Filed:

Apr 2, 2012

Appl. No.:

13/437557

Inventors:

Lei Yu - Carlsbad CA, US
Gang Zhao - Vista CA, US
Sang Van - San Diego CA, US
Sanjib Kumar Das - Oceanside CA, US
Fu Chen - Carlsbad CA, US
Yi Jin - Carlsbad CA, US
Xiaoli Fu - Vista CA, US

Assignee:

Nitto Denko Corporation - Osaka

International Classification:

A61K 47/48
A61K 49/12
A61P 35/00
C08G 69/48

US Classification:

424 9365, 525419, 424 7817

Abstract:

Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.

US Patent:

20210315248, Oct 14, 2021

Filed:

Apr 10, 2020

Appl. No.:

16/846072

Inventors:

- Los Angeles CA, US
Fu Chen - Hacienda Heights CA, US

Assignee:

82 Labs Inc. - Los Angeles CA

International Classification:

A23L 33/105
A23L 2/56

Abstract:

A method of extracting includes crushing to form a crude powder. An ethanol/water solution is used in an extraction tank to create an extracted solution, which is de-colorized using activated carbon. The extracted solution is concentrated and filtered, after which beta-cyclodextrin is added, resulting in a guest/host molecular complex solution. This solution is spray dried, resulting in a DHM rich solution. A beverage additive may include a dihydromyricetin (DHM)/beta-cyclodextrin molecular complex, wherein the DHM/beta-cyclodextrin molecular complex is a guest/host molecular complex, wherein DHM is present in an amount of at least 35 w/w %, and wherein the beverage additive is completely water soluble.

US Patent:

20200246485, Aug 6, 2020

Filed:

Jan 31, 2019

Appl. No.:

15/929100

Inventors:

- Los Angeles CA, US
Fu Chen - Hacienda Heights CA, US

International Classification:

A61K 47/69
A61K 47/12
A61K 47/22
A61K 47/26
A61K 31/352
A61K 9/08

Abstract:

A method of generating a soluble dihydromyricetin formulation may involve generating an acidic solution with a pH ranging between 2-7 pH in a reaction vessel by combining an organic acid in an aqueous solution at a first temperature range. The method may then generate a solvent mixture by combining the acidic solution with a sugar. The method may then heat the solvent mixture to a boil and then adjust the heat to the first temperature range generating a heated solvent mixture. The method may then combine cyclodextrin and dihydromyricetin (DHM) with the heated solvent mixture forming a DHM solution. The method may then mix the DHM solution at a first speed for a first time interval in a mixer. The method may then heat a mixed DHM solution at a second temperature range for a second time interval.