Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Das - Oceanside CA, US Zhongling Feng - San Diego CA, US Xiaoli Fu - Vista CA, US Xinghe Wang - San Diego CA, US Yi Jin - Carlsbad CA, US Fu Chen - Carlsbad CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 49/10 A61K 49/00 A61K 31/785
US Classification:
424009322, 424009600, 424078270, 525054100
Abstract:
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Kumar Das - Oceanside CA, US Fu Chen - Carlsbad CA, US Yi Jin - Carlsbad CA, US Xiaoli Fu - Vista CA, US
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Fu Chen - Carlsbad CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 9/127 A61K 31/7088
US Classification:
424450, 514 44 R, 514 44 A, 424 783
Abstract:
Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.
Padmanabh Chivukula - San Diego CA, US Jian Liu - San Diego CA, US Akinobu Soma - Carlsbad CA, US Keisaku Okada - San Diego CA, US Sang Van - San Diego CA, US Julia Zhu - Escondido CA, US Nianchun Ma - Oceanside CA, US Chen-Chang Lee - Oceanside CA, US Fu Chen - Carlsbad CA, US Lei Yu - Carlsbad CA, US
Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Kumar Das - Oceanside CA, US Fu Chen - Carlsbad CA, US Yi Jin - Carlsbad CA, US Xiaoli Fu - Vista CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 47/48 A61K 49/12 A61P 35/00 C08G 69/48
US Classification:
424 9365, 525419, 424 7817
Abstract:
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.
424450, 514 44 R, 514 44 A, 514725, 514559, 514552
Abstract:
Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.