Gang J Chen

US Patent:

7512508, Mar 31, 2009

Filed:

Sep 6, 2005

Appl. No.:

11/221395

Inventors:

Janusz Rajski - West Linn OR, US
Gang Chen - Wilsonville OR, US
Martin Keim - Sherwood OR, US
Nagesh Tamarapalli - Wilsonville OR, US
Manish Sharma - Wilsonville OR, US
Huaxing Tang - Wilsonville OR, US

International Classification:

G01R 31/26
G06F 11/22

US Classification:

702118, 702181, 702 81, 438 14

Abstract:

Methods, apparatus, and systems for computing and analyzing integrated circuit yield and quality are disclosed herein. For example, in one exemplary method disclosed herein information is received from processing test responses of integrated circuits designed for functional use in electronic devices. In this embodiment, the information is indicative of integrated circuit failures observed during testing of the integrated circuits and of possible yield limiting factors causing the integrated circuit failures. Probabilities that one or more of the possible yield limiting factors in the integrated circuits actually caused the integrated circuit failures are determined by statistically analyzing the received information. The probabilities that one or more possible yield limiting factors actually caused the integrated circuit failures are reported. Tangible computer-readable media comprising computer-executable instructions for causing a computer to perform any of the described methods are also disclosed.

US Patent:

7531166, May 12, 2009

Filed:

Jun 21, 2006

Appl. No.:

11/472813

Inventors:

Linda Masat - Oakland CA, US
Mary Haak-Frendscho - Newark CA, US
Gang Chen - San Diego CA, US
Arnold Horwitz - San Leandro CA, US
Marina Roell - Concord CA, US

Assignee:

XOMA Technology, Ltd. - Berkely CA

International Classification:

C07K 16/24
A61K 39/395

US Classification:

424 852, 5303871, 5303881

Abstract:

An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7582742, Sep 1, 2009

Filed:

Jul 18, 2008

Appl. No.:

12/218914

Inventors:

Linda Masat - Oakland CA, US
Mary Haak-Frendscho - Newark CA, US
Gang Chen - San Diego CA, US
Arnold Horwitz - San Leandro CA, US
Marina Roell - Concord CA, US

Assignee:

XOMA Technology Ltd. - Berkeley CA

International Classification:

C12N 5/10
C12N 15/13
C12N 15/63

US Classification:

536 2353, 435325, 4352523, 4353201

Abstract:

Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO:28, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide is provided. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7695717, Apr 13, 2010

Filed:

Jul 18, 2008

Appl. No.:

12/218997

Inventors:

Linda Masat - Oakland CA, US
Mary Haak-Frendscho - Newark CA, US
Gang Chen - San Diego CA, US
Arnold Horwitz - San Leandro CA, US
Marina Roell - Concord CA, US

Assignee:

XOMA Technology Ltd. - Berkeley CA

International Classification:

A61K 39/395

US Classification:

4241411, 4241451, 4241391

Abstract:

Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO:28, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide is provided. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7744865, Jun 29, 2010

Filed:

May 11, 2009

Appl. No.:

12/463741

Inventors:

Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US

Assignee:

Xoma Technology Ltd. - Berkeley CA

International Classification:

C07K 16/24
A61K 39/395

US Classification:

424 852, 5303871, 5303881

Abstract:

An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 8 and SEQ ID NO: 9, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7744866, Jun 29, 2010

Filed:

May 11, 2009

Appl. No.:

12/463844

Inventors:

Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US

Assignee:

XOMA Technology Ltd. - Berkeley CA

International Classification:

C07K 16/24
A61K 39/395

US Classification:

424 852, 5303871, 5303881

Abstract:

An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 26 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7829093, Nov 9, 2010

Filed:

May 11, 2009

Appl. No.:

12/464006

Inventors:

Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US

Assignee:

Xoma Technology Ltd. - Berkeley CA

International Classification:

A61K 39/395

US Classification:

4241451, 4241301, 4241391, 4241411, 514885

Abstract:

Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO: 15 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

US Patent:

7829094, Nov 9, 2010

Filed:

May 11, 2009

Appl. No.:

12/464061

Inventors:

Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US

Assignee:

Xoma Technology Ltd. - Berkeley CA

International Classification:

A61K 39/395

US Classification:

4241451, 4241301, 4241391, 4241411, 514885

Abstract:

Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO: 15 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.