Gang N Li

US Patent:

7378525, May 27, 2008

Filed:

Dec 23, 2003

Appl. No.:

10/744585

Inventors:

Bing Guan - Chestnut Hill MA, US
Charles Minor - Kingston MA, US
Mingshi Dai - Billerica MA, US
Shomir Ghosh - Brookline MA, US
Tracy J. Jenkins - Belmont MA, US
Gang Li - Framingham MA, US
Douglas F. Burdi - Arlington MA, US
Robert A. Bennett - Milford MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 211/06
C07D 211/68

US Classification:

546195, 546192

Abstract:

Disclosed are CCR8 inhibitors represented by Structural Formulas (I):The variables in Structural Formula (I) are described herein. Also disclosed are methods of treating a subject with a CCR8 mediated condition, especially asthma, by administering one of the disclosed CCR8 inhibitors to the subject.

US Patent:

7491827, Feb 17, 2009

Filed:

Jul 14, 2004

Appl. No.:

10/891362

Inventors:

Mingshi Dai - Billerica MA, US
Bing Guan - Needham MA, US
Robert A. Bennett - Milford MA, US
Douglas F. Burdi - Arlington MA, US
Shomir Ghosh - Brookline MA, US
Gang Li - Westborough MA, US
Charles Minor - Kingston MA, US
Tracy J. Jenkins - Belmont MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 211/06
C07D 215/38
C07D 413/00
C07D 239/02

US Classification:

546206, 546158, 546169, 544129, 544298

Abstract:

The present invention provides compounds of general formula I:.

US Patent:

7565610, Jul 21, 2009

Filed:

Jun 16, 2004

Appl. No.:

10/869807

Inventors:

Gang Li - Needham MA, US
Lee W. Sapiro - Hudson MA, US

Assignee:

EMC Corporation - Hopkinton MA

International Classification:

G06F 15/177
G06F 15/173

US Classification:

715736, 715733, 715734, 715738, 715969, 709223, 709224, 714 4, 714 47

Abstract:

A method and apparatus displays time-based performance information for network objects to facilitate identification of a root cause of one or more triggers.

US Patent:

7998952, Aug 16, 2011

Filed:

Dec 4, 2009

Appl. No.:

12/631144

Inventors:

Indu T. Bharathan - Cambridge MA, US
Matthew Duffey - Boston MA, US
Amy Elder - Arlington MA, US
Jianping Guo - Winchester MA, US
Gang Li - Westborough MA, US
Dominic Reynolds - Stoneham MA, US
Francois Soucy - Stoneham MA, US
Tricia J. Vos - Medford MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 487/04
A61K 31/55

US Classification:

51421206, 540521

Abstract:

This invention provides compounds of formula I:.

US Patent:

8063222, Nov 22, 2011

Filed:

Aug 27, 2008

Appl. No.:

12/229818

Inventors:

Mingshi Dai - Lexington MA, US
Bing Guan - Needham MA, US
Robert A. Bennett - Milford MA, US
Douglas F. Burdi - Arlington MA, US
Shomir Ghosh - Brookline MA, US
Gang Li - Westborough MA, US
Charles A. Minor - Kingston MA, US
Tracy J. Jenkins - Belmont MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 215/38

US Classification:

546159, 546163, 514312

Abstract:

The present invention provides compounds of general formula I:or a pharmaceutically acceptable salt thereof, wherein R, X, Z, R, X, Ar, n, Rand Rare defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.

US Patent:

8268992, Sep 18, 2012

Filed:

Jun 30, 2011

Appl. No.:

13/173161

Inventors:

Indu T. Bharathan - Cambridge MA, US
Matthew Duffey - Boston MA, US
Amy Elder - Arlington MA, US
Jianping Guo - Winchester MA, US
Gang Li - Westborough MA, US
Dominic Reynolds - Stoneham MA, US
Francois Soucy - Stoneham MA, US
Tricia J. Vos - Medford MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 487/04

US Classification:

540521

Abstract:

This invention provides compounds of formula I:.

US Patent:

8507667, Aug 13, 2013

Filed:

Aug 9, 2012

Appl. No.:

13/570486

Inventors:

Indu T. Bharathan - Cambridge MA, US
Matthew O. Duffey - Boston MA, US
Amy M. Elder - Arlington MA, US
Jianping Guo - Winchester MA, US
Gang Li - Westborough MA, US
Dominic Reynolds - Stoneham MA, US
Francois Soucy - Stoneham MA, US
Tricia J. Vos - Boston MA, US

Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

C07D 487/04

US Classification:

540521

Abstract:

This invention provides compounds of formula I:.

US Patent:

20020029226, Mar 7, 2002

Filed:

Sep 5, 2001

Appl. No.:

09/947637

Inventors:

Gang Li - Castro Valley CA, US
Xiaoming Zheng - Albany CA, US
Kenneth Leonard - Hillsborough CA, US

International Classification:

G06F017/30

US Classification:

707/104100, 707/001000, 701/208000, 707/010000

Abstract:

A method and system for taking data in any format, either in a database such as Oracle, SQL, or another common database, and dynamically combining it with geographic information, i.e., a map or aerial or satellite photograph or other image, allows the user to display that data on a map, to analyze that data geographically or spatially or merely to provide information from certain locations. The result can be presented to the user as a single image that can, if desired, be interactive, allowing the user to access additional information not displayed or not capable of displaying on the map.