Gary R Elliott

US Patent:

7314886, Jan 1, 2008

Filed:

Oct 1, 2004

Appl. No.:

10/957039

Inventors:

Qi Chao - San Diego CA, US
Gary T. Elliott - San Diego CA, US
Lorenzo Leoni - Lodrino, CH
Mimi K. Phillips - San Diego CA, US

Assignee:

Cephalon, Inc. - Frazer PA

International Classification:

A61K 31/407
C07D 491/052

US Classification:

514411, 548432

Abstract:

Provided herein are indole derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

US Patent:

7446122, Nov 4, 2008

Filed:

Oct 1, 2004

Appl. No.:

10/956668

Inventors:

Qi Chao - San Diego CA, US
Gary T. Elliott - San Diego CA, US
Lorenzo Leoni - Lodrino, CH

Assignee:

Cephalon, Inc. - Frazer PA

International Classification:

A61K 31/407
A61K 31/4439
C07D 491/052
C07D 401/14

US Classification:

514411, 514338, 548432, 5462767

Abstract:

Provided herein are indole derivatives, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

US Patent:

20060041013, Feb 23, 2006

Filed:

Jun 14, 2005

Appl. No.:

11/153640

Inventors:

Jason Brittain - El Cajon CA, US
Joe Franklin - San Diego CA, US
Lorenzo Leoni - Lodrino, CH
Christina Niemeyer - Poway CA, US
Gary Elliott - San Diego CA, US

International Classification:

A61K 31/21

US Classification:

514509000

Abstract:

Stable liquid formulations of the anti-tumor agent L-alanosine are described. These formulations preferably comprise L-alanosine in an aqueous environment having a basic pH, preferably in the range of about pH 8-9. The alanosine formulations and compositions disclosed herein can be used for various purposes, including the treatment of various cancers, particularly those that are deficient in methylthioadenosine phophorylase (MTAP) enzymatic activity. Also described are methods for the treatment of diseases susceptible to treatment with alanosine, e.g., certain cancers, particularly those characterized by tumor cells that are MTAP deficient, wherein a patient is administered L-alanosine, alone or as part of a combination therapy with a second chemotherapeutic agent.

US Patent:

20060128777, Jun 15, 2006

Filed:

Nov 4, 2005

Appl. No.:

11/267010

Inventors:

Heather Bendall - Del Mar CA, US
Gary Elliott - San Diego CA, US
Lorenzo Leoni - Lodrino, CH
Christina Niemeyer - Poway CA, US
Pratik Multani - San Diego CA, US

International Classification:

A61K 31/4184

US Classification:

514394000

Abstract:

Methods and compositions for treating cancers characterized by death-resistant cancer cells are described. In general, such methods involve administration of a therapeutically effective amount of a compound that induces mitotic catastrophe in the some, and preferably most or all, of the cancerous cells. Methods for assessing the efficacy of such treatments are also provided.

US Patent:

20090196930, Aug 6, 2009

Filed:

Dec 24, 2008

Appl. No.:

12/343920

Inventors:

Mark W. Surber - San Diego CA, US
Gary T. Elliott - San Diego CA, US
Geoffrey Eugene Barker - Carlsbad CA, US

Assignee:

Aires Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 9/14
A61K 33/00
A61P 11/00
A61M 15/00

US Classification:

424489, 424718, 12820315

Abstract:

Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.

US Patent:

20090209606, Aug 20, 2009

Filed:

Feb 18, 2009

Appl. No.:

12/372910

Inventors:

Heather Helene Bendall - Del Mar CA, US
Gary T. Elliott - San Diego CA, US
Lorenzo M. Leoni - Lodrino, CH
Christina Carol Niemeyer - Poway CA, US
Pratik S. Multani - San Diego CA, US

International Classification:

A61K 31/4184
A61P 35/00

US Classification:

514394

Abstract:

Methods and compositions for treating cancers characterized by death-resistant cancer cells are described. In general, such methods involve administration of a therapeutically effective amount of a compound that induces mitotic catastrophe in the some, and preferably most or all, of the cancerous cells. Methods for assessing the efficacy of such treatments are also provided.

US Patent:

20130028942, Jan 31, 2013

Filed:

Sep 25, 2012

Appl. No.:

13/626445

Inventors:

AIRES PHARMACEUTICALS, INC. - San Diego CA, US
GARY T. ELLIOTT - SAN DIEGO CA, US

Assignee:

AIRES PHARMACEUTICALS, INC. - SAN DIEGO CA

International Classification:

A61K 33/00
A61P 9/12
A61P 9/10
A61K 9/14

US Classification:

424400, 424718

Abstract:

Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.

US Patent:

20220356319, Nov 10, 2022

Filed:

Jul 11, 2022

Appl. No.:

17/862117

Inventors:

- San Diego CA, US
Hayley Ann REECE - Dalkeith, GB
Joseph Edward Gordon BENSON - Edinburgh, GB
Sarah COLLINS - Edinburgh, GB
Gary T. ELLIOTT - San Diego CA, US
Mireille GILLINGS - San Diego CA, US
Robert GOODENOW - San Diego CA, US
Curtis TYREE - San Diego CA, US

International Classification:

C08J 9/14
C08J 9/00

Abstract:

Sulcardine salts other than sulfuric acid salts of sulcardine, including crystalline sulcardine salts, are provided herein. Pharmaceutical compositions comprising such salts and methods of treating arrhythmias comprising administering effective amounts of such salts are also provided.