Gary Gates - Hatboro PA, US Chandrasekhar Satishchandran - Worcester MA, US
Assignee:
Veritas Bio LLC - Plymouth Meeting PA
International Classification:
C12N 15/74 C12N 15/63 C12N 1/00
US Classification:
435476, 435471, 4353201, 435243
Abstract:
This invention provides a host-vector complementation system, which permits selection of vector-carrying host cells, without requiring an antibiotic resistance gene. In some embodiments, this system utilizes a host which is guaB deficient and vectors that carry and express the guaB gene. The invention also discloses methods of making and using the system.