George M Michaels

US Patent:

7026026, Apr 11, 2006

Filed:

Dec 16, 2002

Appl. No.:

10/320937

Inventors:

David A. Ferrera - San Francisco CA, US
George C. Michaels - Westford MA, US
Ralph J. Barry - Hudson MA, US
Lixiao Wang - Maple Grove MN, US
Jianhua Chen - Plymouth MN, US

Assignee:

Boston Scientific Scimed, Inc. - Maple Grove MN

International Classification:

A61M 25/10

US Classification:

428 352, 428 355, 428 3691, 428483, 525165, 525178, 604 9301, 604 9601, 60410306, 60410309, 60410311, 264108

Abstract:

Balloons for use on medical devices such as catheter balloons are formed from polymer blend products which include a liquid crystal polymer (LCP), a crystallizable thermoplastic polymer, especially thermoplastic polyesters such as PET, and a compatabilizer. The compatabilizer may be an ethylene-maleic anhydride copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate-maleic anhydride terpolymer, an ethylene-methyl-methacrylic acid terpolymer, an acrylic rubber, an ethylene-ethyl acrylate-glycidyl methacrylate terpolymer or a mixture of two or more such polymers.

US Patent:

7613571, Nov 3, 2009

Filed:

Jul 27, 2001

Appl. No.:

09/916709

Inventors:

Michael D. Doyle - Wheaton IL, US
Betsey S. Williams - Auburndale MA, US
George S. Michaels - Chesterfield MO, US

International Classification:

G01N 33/48
G01N 33/50

US Classification:

702 19, 435 6, 435 71, 703 1

Abstract:

A method of morphological reconstruction of biological activity in a tissue sample maps biological data resulting from analysis of tissue samples onto a 3-D morphological rendering of the biological sample. Each slice in a set of histological slices, indexed by a first index, is micro dissected into micro samples indexed by a pair of first and second indices. The indices are utilized to spatially map biological data to the 3-D rendering.

US Patent:

7894997, Feb 22, 2011

Filed:

Oct 28, 2009

Appl. No.:

12/607577

Inventors:

Michael D. Doyle - Wheaton IL, US
Betsey S. Williams - Auburndale MA, US
George S. Michaels - Chesterfield MO, US

International Classification:

G01N 33/48

US Classification:

702 19, 435 6, 435 71, 703 1, 703 2, 703 11, 702152

Abstract:

A method of morphological reconstruction of biological activity in a tissue sample maps biological data resulting from analysis of tissue samples onto a 3-D morphological rendering of the biological sample. Each slice in a set of histological slices, indexed by a first index, is micro dissected into micro samples indexed by a pair of first and second indices. The indices are utilized to spatially map biological data to the 3-D rendering.

US Patent:

20010019751, Sep 6, 2001

Filed:

Mar 19, 2001

Appl. No.:

09/810361

Inventors:

David Ferrera - San Francisco CA, US
George Michaels - Westford MA, US
Ralph Barry - Hudson MA, US
Lixiao Wang - Maple Grove MN, US
Jianhua Chen - Plymouth MN, US

International Classification:

B32B001/08

US Classification:

428/035200, 428/036900

Abstract:

Balloons for use on medical devices such as catheter balloons are formed from polymer blend products which include a liquid crystal polymer (LCP), a crystallizable thermoplastic polymer, especially thermoplastic polyesters such as PET, and a compatabilizer. The compatabilizer may be an ethylene-maleic anhydride copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate-maleic anhydride terpolymer, an ethylene-methyl-methacrylic acid terpolymer, an acrylic rubber, an ethylene-ethyl acrylate-glycidyl methacrylate terpolymer or a mixture of two or more such polymers.

US Patent:

20110196663, Aug 11, 2011

Filed:

Feb 16, 2011

Appl. No.:

13/029084

Inventors:

Michael D. Doyle - Wheaton IL, US
Betsey S. Williams - Auburndale MA, US
George S. Michaels - Chesterfield MO, US

International Classification:

G06G 7/60

US Classification:

703 11

Abstract:

A method of morphological reconstruction of biological activity in a tissue sample maps biological data resulting from analysis of tissue samples onto a 3-D morphological rendering of the biological sample. Each slice in a set of histological slices, indexed by a first index, is micro dissected into micro samples indexed by a pair of first and second indices. The indices are utilized to spatially map biological data to the 3-D rendering.

US Patent:

62420631, Jun 5, 2001

Filed:

Sep 10, 1997

Appl. No.:

8/926905

Inventors:

David A. Ferrera - San Francisco CA
George C. Michaels - Westford MA
Ralph J. Barry - Hudson MA
Lixiao Wang - Maple Grove MN
Jianhua Chen - Plymouth MN

Assignee:

SciMed Life Systems, Inc. - Maple Grove MN

International Classification:

A61M 2510
C08L 6702
C08L 7700

US Classification:

428 352

Abstract:

Balloons for use on medical devices such as catheter balloons are formed from polymer blend products which include a liquid crystal polymer (LCP), a crystallizable thermoplastic polymer, especially thermoplastic polyesters such as PET, and a compatabilizer. The compatabilizer may be an ethylene-maleic anhydride copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate copolymer, an ethylene-methyl acrylate-maleic anhydride terpolymer, an ethylene-methyl-methacrylic acid terpolymer, an acrylic rubber, an ethylene-ethyl acrylate-glycidyl methacrylate terpolymer or a mixture of two or more such polymers.

US Patent:

D3154491, Mar 19, 1991

Filed:

May 15, 1989

Appl. No.:

7/352214

Inventors:

George G. Michaels - Atherton CA
Peter H. Muller - Los Gatos CA

US Classification:

D 4104

US Patent:

50402609, Aug 20, 1991

Filed:

Mar 16, 1989

Appl. No.:

7/324479

Inventors:

George G. Michaels - Atherton CA

International Classification:

A46B 904

US Classification:

151671

Abstract:

A toothbrush head which is effective for cleaning and polishing teeth and massaging and stimulating the gums, without injury to hard and soft tissue and is durable. The head includes a plurality of integral projections parallel to each other and extending outwardly from a pad. Each projection is constructed of a thermoplastic elastomer providing a high coefficient of friction between the projections and tooth enamel and cementum. The tip and side surfaces of the projections have substantially identical coefficients of friction between the respective surfaces and the tooth's enamel/cementum. At least a portion of the plurality of projections have beveled edges. The projections having beveled edges are preferably arranged in pairs. Each projection of each pair has a beveled edge oriented so as to be positioned in facing relationship with the other projection of the pair. The pairs are configured as facing truncated cylinders.