George William Rozakis

US Patent:

6364871, Apr 2, 2002

Filed:

Jul 14, 1999

Appl. No.:

09/284842

Inventors:

Nicholas Sotiropoulos - Glen Mills PA
Gregory Berlin - West Chester PA
George Rozakis - North Olmsted OH

Assignee:

Apollo Vision, Inc. - Glen Mills PA

International Classification:

A61B 1700

US Classification:

606 5, 606 4

Abstract:

This invention is a method for sculpturing a laser beam ( ) in a predetermined pattern using a device ( ) between the laser source ( ) and the target ( ). The method comprises a series of sequential steps in which at least two regions of the cornea ( ) are each exposed to increasingly larger portions of the laser beam ( ). In the preferred embodiment, two pairs of complementary regions of the cornea ( ) will be sequentially exposed to laser radiation. In each such region, a first part will be exposed to a substantially segmental portion of the beam ( ), and then at least another larger substantially segmental portion of the beam ( ) in which the larger segmental portion, includes the smaller segmental portion. In the preferred embodiment, the target ( ) is the human eye, and the predetermined pattern is intended to shape the eye to treat it for astigmatism, myopia, or hyperopia.

US Patent:

6428574, Aug 6, 2002

Filed:

Jan 18, 2000

Appl. No.:

09/484544

Inventors:

George W. Rozakis - North Olmsted OH

Assignee:

Medennium, Inc. - Irvine CA

International Classification:

A61F 216

US Classification:

623 628

Abstract:

The present application discloses a phakic intraocular lens (IOL) for the correction of visual disorders such as myopia, hyperopia, astigmatism and presbyopia. The lens is made from a biocompatible, elastomeric material such as silicone. The lens further includes one or more annular surfaces that protrude from the anterior surface of the lens or surrounds the lens such that when placed in the eye, it makes contact with the iris. As the iris dilates and constricts, the contact with the iris places a centering force on the implanted lens. The lens is not in contact with the natural lens of the eye and floats in the posterior chamber without insult or abrasion to surrounding tissue.

US Patent:

7521020, Apr 21, 2009

Filed:

Oct 9, 2003

Appl. No.:

10/682168

Inventors:

Miklos Gratzl - Mayfield Heights OH, US
Koji Tohda - Mayfield Heights OH, US
George Rozakis - Lakewood OH, US

Assignee:

Case Western Reserve University - Cleveland OH

International Classification:

B01L 3/02

US Classification:

422100, 422 99, 73863, 436180

Abstract:

A burette () suitable for delivery of a reagent into a target solution () employs diffusion for delivering the reagent. The reagent is in the form of a solution, which is combined with a matrix material (), such as a gel or porous ceramic. A membrane () covers a delivery outlet () to the burette. In one embodiment, the delivery outlet comprises a plurality of fine bores (), each one filled with or covered by a membrane (). Stirring of the burette or target solution is achieved with a stirring means (). A heating or cooling means () heats a tip () of the burette.

US Patent:

7964390, Jun 21, 2011

Filed:

Feb 3, 2005

Appl. No.:

11/050584

Inventors:

George Rozakis - Lakewood OH, US
Miklos Gratzl - Mayfield Heights OH, US
Jian Yang - Mayfield Heights OH, US

Assignee:

Case Western Reserve University - Cleveland OH

International Classification:

C12M 1/34
C12M 3/00
G01N 21/76

US Classification:

4352887, 4352872, 4352879, 4352884, 435808, 436172, 422 8205, 422 8206, 422 8207, 600347

Abstract:

A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is supported by the body. The sensing system exhibits a detectable change when the probe is exposed to the analyte in the fluid. The sensing system may include an enzyme capable of catalyzing a reaction of the analyte to form a reaction product and a dye system which absorbs in the infrared region of the spectrum in response to the reaction product.

US Patent:

20010031959, Oct 18, 2001

Filed:

Dec 29, 2000

Appl. No.:

09/752273

Inventors:

George Rozakis - Lakewood OH, US
Guillermo Avalos - Guadalajara JAL, MX

International Classification:

A61B018/20

US Classification:

606/005000

Abstract:

A system for correcting presbyopia provides a laser adapted to sculpt the cornea in two concentric zones. The first larger zone is treated with a positive diopter correction to allow eye to focus on near objects. A second smaller zone is then treated with a negative diopter correction to allow the cornea to focus on far objects. In one embodiment, the system directs the laser in a series of collapsing crescents to sculpt the zones.

US Patent:

20010047204, Nov 29, 2001

Filed:

Feb 28, 2001

Appl. No.:

09/795912

Inventors:

Stephen Zhou - Irvine CA, US
George Rozakis - North Olmsted OH, US

Assignee:

Medennium, Inc.

International Classification:

A61F002/16

US Classification:

623/006110, 623/905000

Abstract:

A method for selecting the size of a phakic intraocular lens positioned in the eye between the iris and the natural lens, is disclosed. In this method, the white to white distance of the patient's eye is measured and the length of the lens is based on that measurement. A photographic method of measurement is disclosed.

US Patent:

20020120255, Aug 29, 2002

Filed:

Mar 5, 2002

Appl. No.:

09/942375

Inventors:

Nicholas Sotiropoulos - Glen Mills PA, US
Gregory Berlin - West Chester PA, US
George Rozakis - North Olmsted OH, US

International Classification:

A61B018/20

US Classification:

606/005000

Abstract:

Disclosed are methods and devices which comprise providing a laser beam having a pre-defined shape along a beam axis and exposing a plurality of corneal regions to a plurality of asymmetrical laser beam subportions to affect the shape of said cornea without introducing any substantial asymmetry to the shape of said cornea.

US Patent:

20030033012, Feb 13, 2003

Filed:

Oct 15, 2002

Appl. No.:

10/272019

Inventors:

Stephen Zhou - Irvine CA, US
George Rozakis - North Olmsted OH, US

International Classification:

A61F002/16
A61F009/00
A61F011/00

US Classification:

623/006110, 623/907000

Abstract:

A method for selecting the size of a phakic intraocular lens positioned in the eye between the iris and the natural lens, is disclosed. In this method, the white-to-white distance of the patient's eye is measured and the length of the lens is based on that measurement. A photographic method of measurement is disclosed.