George M Walker

Address:

2699 N Tenaya Way, Las Vegas, NV 89128

VIN:

JTLKE50E291089553

Make:

SCION

Model:

XB

Year:

2009

US Patent:

RE39885, Oct 16, 2007

Filed:

May 20, 1998

Appl. No.:

09/082247

Inventors:

James G. Nadeau - Ellicott City MD, US
George T. Walker - Chapel Hill NC, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435 6, 435 912

Abstract:

Methods for detecting, immobilizing or localizing primer extension products of a Strand Displacement Amplification reaction which are coupled to, and an indication of, amplification of the target sequence. The primer extension products are secondary, target-specific DNA products generated concurrently with SDA of the target sequence and can therefore be used to detect and/or measure target sequence amplification in real-time. In general, the secondary amplification products are not amplifiable and remain inert in the SDA reaction after they are formed without interfering with amplification of the target sequence. The secondary amplification products may be designed or modified to contain special features to facilitate their detection, immobilization or localization.

US Patent:

20200286590, Sep 10, 2020

Filed:

Nov 11, 2019

Appl. No.:

16/679927

Inventors:

- Gaithersburg MD, US
Vadim Sapiro - North Potomac MD, US
George Terrance Walker - Chevy Chase MD, US
Alex Saeed - Germantown MD, US

Assignee:

OpGen, Inc. - Gaithersburg MD

International Classification:

G16B 40/00
G16B 20/00
G16B 45/00
G16H 50/80
G16B 20/40

Abstract:

Systems, apparatus, and methods are disclosed for generating a resistome profile for a subject, monitoring an infection state of one or more subjects, and/or identifying a potential infection outbreak at a facility, for example, by obtaining first data representative of at least one measure of antibiotic resistance of an organism from a first sample, identifying the organism, determining at least one of an antibiotic susceptibility phenotype, an identity of an antibiotic resistance gene, and an antibiotic to which the organism is non-susceptible, generating and comparing a first pattern to at least one known pattern to determine and generate a profile uniqueness identifier indicating a degree of similarity above a threshold between the first pattern and the at least one known pattern.