Gerald Patrick O'Hara

US Patent:

46861025, Aug 11, 1987

Filed:

Apr 12, 1984

Appl. No.:

6/599318

Inventors:

Mary B. Ritchey - Norwood NJ
Francis R. Cano - Mahwah NJ
Gerald J. O'Hara - Pearl River NY
James D. English - Oradell NJ
Wenlii Lin - New City NY

Assignee:

American Cyanamid Company - Stamford CT

International Classification:

A61K 39116

US Classification:

424 92

Abstract:

A multivalent pneumococcal vaccine consisting of immunogenic amounts of purified pneumococcal capsular polysaccharide (substantially absent "C" polysaccharide) of pneumococcal types (Danish designation) 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F and 33F, and from none to one or both of 6A and 25, and combinations thereof and methods of purifying pneumococcal capsular polysaccharide types 3, 5, 9V, 10A, 11A, 15B, 17F, 19A, 22F and 33F.