Teryl K. Frey - Atlanta GA Geraldina Dominguez - Tucker GA Chin-Yen Wang - Roswell GA
Assignee:
Georgia State University Research Foundation, Inc. - Atlanta GA
International Classification:
C12N 1500 C12N 700 C12N 1540 C12N 1563
US Classification:
4351723
Abstract:
An infectious rubella virus cDNA clone and entire rubella virus genomic RNA sequence. Non-pathogenic mutants of this clone are useful as vaccines to vaccinate humans, including pregnant or older women, with decreased risk of causing fetal infection, autoimmune disease or neurological symptoms.
Teryl K. Frey - Atlanta GA Geraldina Dominguez - Tucker GA Chin-Yen Wang - Clarkston GA
Assignee:
Georgia State Research Foundation, Inc. - Atlanta GA
International Classification:
C12N 1500 C12N 700 C12N 1540 C12N 1563
US Classification:
4351723
Abstract:
The entire rubella virus genomic RNA has been sequenced. An infectious cDNA clone has been constructed. Mutants of this clone that are rendered non-pathogenic are used as vaccines to vaccinate humans, including pregnant or older women, with decreased risk of causing fetal infection, autoimmune disease or neurological symptoms.