Jacques Banville - St-Hubert, CA Yonghua Gai - Killingworth CT Graham Johnson - Madison CT Fred Christopher Zusi - Hamden CT James R. Burke - Upper Holland PA
Selective inhibitors of the cPLA enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula where (RĂ¢), p, D, Y, Z, R , R and A are as defined in the specification.
Arylalkylbenzofuran Derivatives As Melatonergic Agents
Katherine S. Takaki - Middletown CT Graham Johnson - Madison CT James R. Epperson - Cromwell CT Stephen R. Bertenshaw - Cheshire CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31343
US Classification:
514469, 549467, 549462
Abstract:
Novel benzofuran and dihydrobenzofuran derivatives which have a binding affinity for the human melatonin receptor and, therefore, are useful as melatonergic agents.
Benzoxazole Derivatives As Novel Melatonergic Agents
Katherine S. Takaki - Middletown CT Li-Qiang Sun - Glastonbury CT Graham Johnson - Madison CT Stephen R. Bertenshaw - Cheshire CT Derek Denhart - Durham CT Jie Chen - Madison CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31423
US Classification:
514375, 548217, 548224
Abstract:
Novel benzoxazole derivatives which have a binding affinity for the human melatonin receptor and, therefore, are useful as melatonergic agents.
Roger Hanselmann - Branford CT, US Maxwell M. Reeve - Guilford CT, US Graham Johnson - Madison CT, US
Assignee:
Rib-X Pharmaceuticals, Inc. - New Haven CT
International Classification:
C07D 215/38
US Classification:
546159
Abstract:
The present invention relates to the field of synthesizing anti-infective compounds. More particularly, the invention relates to synthesizing a family of quinolone compounds useful as anti-infective agents. The invention includes a process for preparing a quinolone compound wherein less than about 0. 40% of dimeric impurity of the quinolone is produced.
James Epperson - Cromwell CT Graham Johnson - Madison CT Daniel J. Keavy - Killingworth CT Katherine S. Takaki - Middletown CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 3134 A61K 31335 C07D30777 C07D31770
US Classification:
514463
Abstract:
Novel polycyclic ethyl alkylamides of formula I are active as melatonergic agents. ##STR1## wherein Z=CH (when a double bond is present) or (CH. sub. 2). sub. n, wherein n is 1-4; X=O, CH. sub. 2, or CH (when a double bond is present); R=C. sub. 1-6 alkyl, C. sub. 3-6 cycloalkyl, or C. sub. 1-3 haloalkyl, C. sub. 2-6 alkenyl, C. sub. 2-4 alkoxyalkyl, C. sub. 1-4 trifluoromethylalkyl, C. sub. 1-6 aminoalkyl; and Y=H, C. sub. 1-6 alkoxy or halogen.
John D. Catt - Southington CT Graham Johnson - Madison CT Daniel J. Keavy - Killingworth CT Ronald J. Mattson - Meriden CT Michael F. Parker - Middletown CT Katherine S. Takaki - Middletown CT Joseph P. Yevich - Southington CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D31760 C07D31908 A61K 3136 A61K 3135
US Classification:
514450
Abstract:
Novel derivatives of benzodioxa alkylene ethers are provided which are useful as melatonergic agents.
Marc A. Bruce - Wallingford CT Graham S. Poindexter - Old Saybrook CT Graham Johnson - Madison CT
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31505 C07D40112
US Classification:
514274
Abstract:
The present invention provides a series of non-peptidergic antagonists of NPY comprising piperidine derivatives of 4-phenyl-1,4-dihydropyrimidinones of the Formula I ##STR1## wherein R, R. sup. 1 and R. sup. 2 are defined herein. As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
N-Acyl-2-Aryl Cyclopropylmethylamine Derivatives As Melatonergics
Dr. Johnson graduated from the University of Arkansas College of Medicine at Little Rock in 2011. He works in Philadelphia, PA and specializes in Family Medicine. Dr. Johnson is affiliated with Chestnut Hill Hospital.
University of Birmingham - Medicine, Nottingham High School - Everything!, Lowes Wong Junior School - Everything!, Holy Trinity Infant School - Everything!
About:
Married to Catherine, with a son, Harry. Working as a Emergency Doctor in Nottinghamshire
South Texas College, Texas A&M Kingsville, P.SJ.A North High School, P.SJ.A High
Graham Johnson
Work:
Freelancer
Education:
Flagler College - Fine Art
Tagline:
Artist/Writer attempting to make some comics.
Graham Johnson
Work:
Mine (2012)
About:
Growing old is compulsory - growing up is optional.  I'm Out.
Graham Johnson
Education:
Illinois Institute of Technology - Chemical Engineering
Graham Johnson
About:
So yes. Â I'm an illustration student (well. Â I will be in september) and I draw comics. Â If you feel the need to know more you could always ask? If you'd like to commission me, get in touch vi...
Tagline:
I'm starting to think Google+ was invented to confuse me.
Graham Johnson
About:
Hi,im graham johnson ,owner of doodybeach siargao island surigao del norte philippines,originally from melbourne ,australiaÂ