Gregory J Carroll

US Patent:

20150265691, Sep 24, 2015

Filed:

Sep 14, 2007

Appl. No.:

11/901234

Inventors:

Denong Wang - Palo Alto CA, US
Pavol Kovac - Silver Spring MD, US
Lawrence Steinman - Stanford CA, US
Gregory Carroll - Cincinnati OH, US
Nicholas Turro - Tenafly NJ, US
Jeffrey Koberstein - Sturrs CT, US
Rina Saksena - Sturrs CT, US
Roberto Adamo - Siene, IT

International Classification:

A61K 39/07
G01N 33/68
G01N 33/569
A61K 47/48
C07K 16/12
C07K 16/42

Abstract:

This invention provides a vaccine comprising (i) an anthrose-containing saccharide in an amount effective to enhance immunity against in a subject and (ii) a pharmaceutically acceptable carrier. This invention provides a vaccine comprising (i) a conjugate of an anthrose-containing saccharide in an amount effective to enhance immunity against in a subject, wherein the anthrose-containing saccharide is conjugated to a biomolecule via a linker, and (ii) a pharmaceutically acceptable carrier. This invention provides a method for vaccinating a subject against infection comprising administering to the subject a vaccine comprising (i) an anthrose-containing saccharide in an amount effective to enhance immunity against in the subject and (ii) a pharmaceutically acceptable carrier, in an amount effective to stimulate production of antibodies to spores in the subject, thereby vaccinating the subject against